Our interdisciplinary SMART Center's Neuroscience Core will integrate neuroscience and self-management science to uncover the relationships between brain processes with self-management behaviors. To achieve that goal, the Neuroscience Core will provide SMART Center investigators with cutting-edge technologies and support to obtain real-time measures of brain activity and function associated with self-management behaviors.
Aim 1 provides expertise in the collection, analysis and interpretation of functional magnetic resonance imaging (fMRI) of brain activity.
Aim 2 provides expertise in the collection, analysis and interpretation of electroencephalographic (EEG) measures of cortical neural network activity obtained with Hi-density EEG (128 channels), standard EEG (20 channels), nocturnal EEG (16-20 channels), or EEG assessment of cognition P300 (2-4 channels).
Aim 3 provides expertise in collection, analysis and interpretation of hypothalamic- pituitary axis (HPA) function and stress levels through electrochemiluminescence measures of serum and hair. The Neuroscience Core is guided by neurophysiologic models proposing that activity within specific brain regions, such as the prefrontal cortex, influence a person's critical decision making. Complimentary models guiding Neuroscience Core faculty include consideration of neural activity within multiple cortical networks and their influence upon learning, behavior, and implementing new skills. Neuroscience Core faculty will integrate those models with contemporary models of self-management behaviors to develop new knowledge describing, perhaps for the first time, neural processes involved with self-management behaviors. Our Neuroscience Core faculty's expertise in neuropathology and psychopathology may also contribute to our understanding of sub- clinical or unapparent brain dysfunction that impedes one's ability to learn or perform new self-management strategies. Neuroscience Core faculty will offer laboratory-based training in the application of neuroscience technologies including neurobiology, cognitive neuroscience, neuroimaging, and molecular biology that will be used to assess self-management hypotheses proposed by SMART Center investigators. Additional training opportunities include coursework and workshops in Neurobiology, Cognitive Science, and Genetics, that are currently taught by Neuroscience Core faculty. Expertise residing within the Neuroscience Core will be made available to the general campus community through a service model in which consultation and services can be requested. These will be tracked, quantified, summarized and reported to Administrative and Executive Committees. The Neuroscience Core faculty will also coordinate with the Pilot Cores to review preliminary results from individual Pilot Projects and subsequently develop seminars to address topics of interest to Smart Center investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Center Core Grants (P30)
Project #
1P30NR015326-01
Application #
8821094
Study Section
Special Emphasis Panel (ZNR1-REV-M (17))
Project Start
Project End
Budget Start
2014-09-25
Budget End
2015-07-31
Support Year
1
Fiscal Year
2014
Total Cost
$145,056
Indirect Cost
$53,538
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Moss, Karen O; Still, Carolyn H; Jones, Lenette M et al. (2018) Hypertension Self-Management Perspectives From African American Older Adults. West J Nurs Res :193945918780331
Jones, Lenette M; Veinot, Tiffany C; Pressler, Susan J (2018) Cell Phone Information Seeking Explains Blood Pressure in African American Women. West J Nurs Res 40:617-632
Wright, Kathy D; Still, Carolyn H; Jones, Lenette M et al. (2018) Designing a Cocreated Intervention with African American Older Adults for Hypertension Self-Management. Int J Hypertens 2018:7591289
Jones, Lenette M; Wright, Kathy D; Wallace, McKenzie K et al. (2018) ""Take an opportunity whenever you get it"": Information Sharing among African-American Women with Hypertension. J Assoc Inf Sci Technol 69:168-171
Jones, Lenette M; Veinot, Tiffany; Pressler, Susan J et al. (2018) Exploring Predictors of Information Use to Self-Manage Blood Pressure in Midwestern African American Women with Hypertension. J Immigr Minor Health 20:569-576
Still, Carolyn Harmon; Jones, Lenette M; Moss, Karen O et al. (2018) African American Older Adults' Perceived Use of Technology for Hypertension Self-Management. Res Gerontol Nurs 11:249-256
Jones, Lenette M; Moss, Karen O; Wright, Kathy D et al. (2018) ""Maybe This Generation Here Could Help the Next Generation"": Older African American Women's Perceptions on Information Sharing to Improve Health in Younger Generations. Res Gerontol Nurs 11:39-47
Renna, Megan E; Quintero, Jean M; Soffer, Ariella et al. (2018) A Pilot Study of Emotion Regulation Therapy for Generalized Anxiety and Depression: Findings From a Diverse Sample of Young Adults. Behav Ther 49:403-418
Wright, Kathy; Moore, Shirley M; Morris, Diana Lynn et al. (2017) Geocoding to Manage Missing Data in a Secondary Analysis of Community-Dwelling, Low-Income Older Adults. Res Gerontol Nurs 10:155-161
Musil, Carol M; Givens, Sarah E; Jeanblanc, Alexandra B et al. (2017) Grandmothers and Self-Management of Depressive Symptoms. Arch Psychiatr Nurs 31:234-240

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