Mark Bouzyk, PhD will serve as the Genetics Core Director. Dr. Bouzyk is the director of the Emory Center for Medical Genomics (CMG), which will house and administer the Genetics Core. The core provides state-of-theart laboratory capabilities to enable high throughput genetic linkage and association studies ranging from candidate gene to genomic screens all supported by a robust and flexible data management infrastructure. Dr Bouzyk recently joined the faculty at Emory with a more than eight year track record in a global pharmaceutical company, GlaxoSmithKline, where he served as Director of Genetic Laboratory Sciences leading the company's high throughput genotyping efforts in Europe. During his time in industry, Dr Bouzyk not only established and managed the high throughput genetic laboratories for GSK, including DMA sample management, sequencing and genotyping, he also delivered key processes for candidate gene and whole genome association studies as well as negotiating key scientific &technological agreements for such genetic projects. This has resulted in an annual turnover of more than 10 million genotypes at GSK with significant preliminary association data in several common diseases, such as diabetes and asthma. In his position at Emory, Dr. Bouzyk serves as the link between the faculty utilizing the services of the core and the technicians analyzing the samples. Under his direction, the Center for Medical Genomics has acquired the equipment and personnel necessary to operate as a high-throughput extraction, sequencing, expression and genotyping facility. Dr. Bouzyk is responsible for working with the faculty to develop workflows for the life cycle of each project, to develop methods to ensure high quality of the data produced by the core, and to identify and acquire new technology and equipment.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS055077-05
Application #
8388007
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
2014-05-30
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
5
Fiscal Year
2013
Total Cost
$59,696
Indirect Cost
$21,182
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Umoh, Mfon E; Dammer, Eric B; Dai, Jingting et al. (2018) A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. EMBO Mol Med 10:48-62
Omotade, Omotola F; Rui, Yanfang; Lei, Wenliang et al. (2018) Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. J Neurosci 38:10271-10285
Johnson, Erik C B; Dammer, Eric B; Duong, Duc M et al. (2018) Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Mol Neurodegener 13:52
Srikanth, Priya; Lagomarsino, Valentina N; Pearse 2nd, Richard V et al. (2018) Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry 8:245
Abreha, Measho H; Dammer, Eric B; Ping, Lingyan et al. (2018) Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics 18:e1800108
Gigante, Eduardo D; Long, Alyssa Bushey; Ben-Ami, Johanna et al. (2018) Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response. Dev Biol 437:152-162
Zhao, Kai; Shen, Chengyong; Li, Lei et al. (2018) Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. J Neurosci 38:8860-8873
Gerber, Kyle J; Squires, Katherine E; Hepler, John R (2018) 14-3-3? binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:G?i-AlF4- signaling complex and RGS14 nuclear localization. J Biol Chem 293:14616-14631
Squires, Katherine E; Gerber, Kyle J; Pare, Jean-Francois et al. (2018) Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain. Brain Struct Funct 223:233-253
Yang, Su; Li, Shihua; Li, Xiao-Jiang (2018) Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity. Cell Rep 25:2653-2659.e3

Showing the most recent 10 out of 256 publications