Abstract

Intrauterine growth retardation (IUGR) affects 3-8% of human infants and is responsible for as much as 25% of perinatal mortality. Animal models are lacking for this condition. Squirrel monkeys have several characteristics known to be risk factors for human IUGR. This study assesses the relationship between growth measurements and naturally occurring perinatal mortality in squirrel monkeys. Fetal growth and development studies continued in 1996. A standardized technique for ultrasound examination of the pregnant squirrel monkey was developed that can be performed in awake animals in less than 20 minutes. Over 100 perinatal examinations of pregnant dams were performed that included ultrasound imaging and measurements of fetal growth.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Material Resource Grants (P40)
Project #
5P40RR001254-18
Application #
6280767
Study Section
Project Start
1998-04-01
Project End
1999-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
18
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of South Alabama
Department
Type
DUNS #
City
Mobile
State
AL
Country
United States
Zip Code
36688

  Publications

Lindo, Fiona M; Carr, Emily S; Reyes, Michelle et al. (2015) Randomized trial of cesarean vs vaginal delivery for effects on the pelvic floor in squirrel monkeys. Am J Obstet Gynecol 213:735.e1-8
Raghanti, Mary Ann; Edler, Melissa K; Meindl, Richard S et al. (2014) Humans and great apes share increased neocortical neuropeptide Y innervation compared to other haplorhine primates. Front Hum Neurosci 8:101
Joyce, John S; Dornak, Sarah; Gendron, Jilene M et al. (2014) Lack of association between pelvic outlet diameter and pelvic organ prolapse in squirrel monkeys. Int Urogynecol J 25:1121-6
Hopper, Lm; Holmes, An; Williams, LE et al. (2013) Dissecting the mechanisms of squirrel monkey (Saimiri boliviensis) social learning. PeerJ 1:e13
Freeman, Hani D; Sullivan, Jennifer; Hopper, Lydia M et al. (2013) Different responses to reward comparisons by three primate species. PLoS One 8:e76297
Raghanti, Mary Ann; Conley, Tiffini; Sudduth, Jessica et al. (2013) Neuropeptide Y-immunoreactive neurons in the cerebral cortex of humans and other haplorrhine primates. Am J Primatol 75:415-24
Blomquist, G E; Williams, L E (2013) Quantitative genetics of costly neonatal sexual size dimorphism in squirrel monkeys (Saimiri boliviensis). J Evol Biol 26:756-65
Nehete, Pramod N; Hanley, Patrick W; Nehete, Bharti P et al. (2013) Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis). PLoS One 8:e79836
Hanna, Jandy B; Schmitt, Daniel (2011) Locomotor energetics in primates: gait mechanics and their relationship to the energetics of vertical and horizontal locomotion. Am J Phys Anthropol 145:43-54
Talbot, Catherine F; Freeman, Hani D; Williams, Lawrence E et al. (2011) Squirrel monkeys' response to inequitable outcomes indicates a behavioural convergence within the primates. Biol Lett 7:680-2

Showing the most recent 10 out of 61 publications