Abstract

RARAF has a long history of providing a user-friendly environment with dedicated facilities for the support of biology experiments. In response to user requests, we propose developments in two key areas that will significantly extend experimental capabilities on our microbeam endstations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Biotechnology Resource Grants (P41)
Project #
5P41EB002033-22
Application #
9480437
Study Section
Special Emphasis Panel (ZEB1-OSR-E (M1)P)
Program Officer
Sastre, Antonio
Project Start
Project End
Budget Start
2017-06-01
Budget End
2018-05-31
Support Year
22
Fiscal Year
2017
Total Cost
$187,070
Indirect Cost
$70,064

  Institution

Name
Columbia University (N.Y.)
Department
Type
Domestic Higher Education
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Wu, Jinhua; Hei, Tom K (2018) Focus small to find big - the microbeam story. Int J Radiat Biol 94:782-788
Xu, Y; Randers-Pehrson, G; Marino, S A et al. (2018) A Horizontal Multi-Purpose Microbeam System. Nucl Instrum Methods Phys Res A 888:18-21
Amundson, Sally A (2018) Gene Expression Studies for the Development of Particle Therapy. Int J Part Ther 5:49-59
Broustas, Constantinos G; Harken, Andrew D; Garty, Guy et al. (2018) Identification of differentially expressed genes and pathways in mice exposed to mixed field neutron/photon radiation. BMC Genomics 19:504
England, Matthew J; Bigelow, Alan W; Merchant, Michael J et al. (2017) Automated microbeam observation environment for biological analysis-Custom portable environmental control applied to a vertical microbeam system. Sens Actuators B Chem 239:1134-1143
Olsen, Timothy R; Tapia-Alveal, Claudia; Yang, Kyung-Ae et al. (2017) INTEGRATED MICROFLUIDIC SELEX USING FREE SOLUTION ELECTROKINETICS. J Electrochem Soc 164:B3122-B3129
Wu, Jinhua; Zhang, Qin; Wuu, Yen-Ruh et al. (2017) Cytoplasmic Irradiation Induces Metabolic Shift in Human Small Airway Epithelial Cells via Activation of Pim-1 Kinase. Radiat Res 187:441-453
Broustas, Constantinos G; Xu, Yanping; Harken, Andrew D et al. (2017) Impact of Neutron Exposure on Global Gene Expression in a Human Peripheral Blood Model. Radiat Res 187:433-440
Marino, Stephen A (2017) 50 Years of the Radiological Research Accelerator Facility (RARAF). Radiat Res 187:413-423
Wu, Jinhua; Zhang, Bo; Wuu, Yen-Ruh et al. (2017) Targeted cytoplasmic irradiation and autophagy. Mutat Res 806:88-97

Showing the most recent 10 out of 73 publications