Abstract

Technology Research and Development Project #1 Towards Rapid Continuous Comprehensive MR Imaging: New Methods, New Paradigms, and New Applications TR&D #1 Principal Investigators: Ricardo Otazo, PhD and Daniel K. Sodickson, MD, PhD The broad mission of our Center for Advanced Imaging Innovation and Research (CAI2R) is to bring together collaborative translational research teams for the development of high-impact biomedical imaging technologies, with the ultimate goal of changing day-to-day clinical practice. Technology Research and Development (TR&D) project #1 aims at a new use of time in imaging, deploying leading-edge methods of rapid image acquisition and advanced image reconstruction to replace traditional complex, targeted, and inefficient imaging protocols with simple, comprehensive, volumetric acquisitions that contain rich information about multiple complementary contrasts and diverse dynamics.
Specific aims are as follows: (1) New methods: Develop novel rapid MR acquisition and reconstruction strategies specifically tailored to the needs of collaborative and service projects, taking advantage of compressed sensing, parallel imaging and model-based reconstruction. (2) New paradigm: Establish a new paradigm for MR scanning, using continuously-updated motion-robust comprehensive acquisitions eliminating dead time, coupled with tailored image reconstructions with user- defined contrast and spatiotemporal profiles. (3) New applications: Implement this new scanning paradigm in collaborative and service projects and evaluate its efficacy in routine patient populations for high-volume high-impact clinical applications.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Biotechnology Resource Grants (P41)
Project #
1P41EB017183-01A1
Application #
8794073
Study Section
Special Emphasis Panel (ZEB1-OSR-E (O1))
Project Start
Project End
Budget Start
2014-09-30
Budget End
2015-07-31
Support Year
1
Fiscal Year
2014
Total Cost
$324,636
Indirect Cost
$83,169

  Institution

Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Chen, Gang; Zhang, Bei; Cloos, Martijn A et al. (2018) A highly decoupled transmit-receive array design with triangular elements at 7T. Magn Reson Med 80:2267-2274
Assländer, Jakob; Cloos, Martijn A; Knoll, Florian et al. (2018) Low rank alternating direction method of multipliers reconstruction for MR fingerprinting. Magn Reson Med 79:83-96
Alon, Leeor; Lattanzi, Riccardo; Lakshmanan, Karthik et al. (2018) Transverse slot antennas for high field MRI. Magn Reson Med 80:1233-1242
Feng, Li; Delacoste, Jean; Smith, David et al. (2018) Simultaneous Evaluation of Lung Anatomy and Ventilation Using 4D Respiratory-Motion-Resolved Ultrashort Echo Time Sparse MRI. J Magn Reson Imaging :
Liu, Saifeng; Brisset, Jean-Christophe; Hu, Jiani et al. (2018) Susceptibility weighted imaging and quantitative susceptibility mapping of the cerebral vasculature using ferumoxytol. J Magn Reson Imaging 47:621-633
Leithner, Doris; Moy, Linda; Morris, Elizabeth A et al. (2018) Abbreviated MRI of the Breast: Does It Provide Value? J Magn Reson Imaging :
Khegai, Oleksandr; Madelin, Guillaume; Brown, Ryan et al. (2018) Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T. Magn Reson Med 79:974-980
Wang, Yuan; Wang, Yao; Lui, Yvonne W (2018) Generalized Recurrent Neural Network accommodating Dynamic Causal Modeling for functional MRI analysis. Neuroimage 178:385-402
Assländer, Jakob; Glaser, Steffen J; Hennig, Jürgen (2018) Application of spin echoes in the regime of weak dephasing to T1 -mapping of the lung. Magn Reson Med 79:960-967
Rezaei, Ahmadreza; Deroose, Christophe M; Vahle, Thomas et al. (2018) Joint Reconstruction of Activity and Attenuation in Time-of-Flight PET: A Quantitative Analysis. J Nucl Med 59:1630-1635

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