Abstract

The overall goal of the collaboration efforts of the Yeast Resource Center is to continue refining technologies developed within the center while simultaneously providing access to expertise and resources to the scientific community. Our resource has been an invaluable collaborative resource for the scientific community by making available advanced technologies developed by the center. In the last 5 years our Biomedical Technology Research Resource (BTRR) has had a total of 347 collaborations that are widely distributed throughout the United States. Collaborations differ from our Driving Biomedical Projects in that they don't require the development of new technologies but instead directly apply more established methods that make use of the expertise, instrumentation, software, and protocols facilitated by our resource. We have a history of openly supporting the scientific community by accepting collaborations that align with our expertise. A strength of a ?Yeast? resource center is that we have been a valuable resource and source of collaboration for the yeast scientific community. These collaborations have become an excellent opportunity in refining our established technologies. Once refined, methods often get extended to collaborations in experimental systems beyond yeast as the technology matures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Biotechnology Resource Grants (P41)
Project #
5P41GM103533-24
Application #
9900807
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
24
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

DaRosa, Paul A; Harrison, Joseph S; Zelter, Alex et al. (2018) A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. Mol Cell 72:753-765.e6
Xu, Yi; Ju, Ho-Jong; DeBlasio, Stacy et al. (2018) A Stem-Loop Structure in Potato Leafroll Virus Open Reading Frame 5 (ORF5) Is Essential for Readthrough Translation of the Coat Protein ORF Stop Codon 700 Bases Upstream. J Virol 92:
Burke, Jordan E; Longhurst, Adam D; Merkurjev, Daria et al. (2018) Spliceosome Profiling Visualizes Operations of a Dynamic RNP at Nucleotide Resolution. Cell 173:1014-1030.e17
Xavier, Marina Amaral; Tirloni, Lucas; Pinto, Antônio F M et al. (2018) A proteomic insight into vitellogenesis during tick ovary maturation. Sci Rep 8:4698
Hollmann, Taylor; Kim, Tae Kwon; Tirloni, Lucas et al. (2018) Identification and characterization of proteins in the Amblyomma americanum tick cement cone. Int J Parasitol 48:211-224
Mutlu, Beste; Chen, Huei-Mei; Moresco, James J et al. (2018) Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in C. elegans embryos. Sci Adv 4:eaat6224
Jester, Benjamin W; Tinberg, Christine E; Rich, Matthew S et al. (2018) Engineered Biosensors from Dimeric Ligand-Binding Domains. ACS Synth Biol 7:2457-2467
Kim, Yeoun Jin; Sweet, Steve M; Egertson, Jarrett D et al. (2018) Data-independent acquisition mass spectrometry to quantify protein levels in FFPE tumor biopsies for molecular diagnostics. J Proteome Res :
Keich, Uri; Noble, William Stafford (2018) Controlling the FDR in imperfect matches to an incomplete database. J Am Stat Assoc 113:973-982
Louka, Panagiota; Vasudevan, Krishna Kumar; Guha, Mayukh et al. (2018) Proteins that control the geometry of microtubules at the ends of cilia. J Cell Biol 217:4298-4313

Showing the most recent 10 out of 372 publications