Driving Biological Projects. DBPs ensure that the TRDs address challenges posed by ongoing, funded research on important biomedical problems. The DBP applications include protein structural biology, NMR relaxation studies of biomolecular dynamics, and NMR metabolomics, including a clinical project. The DBPs present challenges that can be addressed using computation as well as offering opportunities for greater advances enabled through novel software and high-performance computation. While the challenges for clinical metabolomics projects are similar to other metabolomics projects, clinical projects have regulatory burdens associated with protected health information (PHI). Developing a HIPPA-compliant instance of NMRbox presents new challenges, but extends the utility of NMRbox to a new constituency, investigators employing NMR in clinical settings. !

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Biotechnology Resource Grants (P41)
Project #
2P41GM111135-06
Application #
9855788
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
DUNS #
022254226
City
Farmington
State
CT
Country
United States
Zip Code
06030
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Nguyen, Khiem; Puthenveetil, Robbins; Vinogradova, Olga (2017) Investigation of the adaptor protein PLIC-2 in multiple pathways. Biochem Biophys Rep 9:341-348

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