This work is focussed on the synthesis of vinblastine type alkaloids for anti-cancer testing, and 18-methoxycoronaridine and congeners for anti-addictive and for HIV-Lychmania inhibition. Syntheses are typically 12 to 25 steps land and require MS characterization of intermediates and products.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR000954-24
Application #
6336796
Study Section
Project Start
2000-08-01
Project End
2001-07-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
24
Fiscal Year
2000
Total Cost
$9,252
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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