Abstract

Since the discovery of the mesoporous silicate molecular sieve MCM-41 in 1992 the mechanism of formation of organic/inorganic mesostructures in general have been a subject of great interest and debate. This silicate material, and its recently prepared transition metal oxide analogues M-TMS1 (M = Nb, Ta, Ti), consist of a hexagonally-packed array of inorganic tubules ranging from 20-100? in diameter and are formed by templating of inorganic oxides onto a self-assembled liquid crystal mesostructure. These well-defined mesoporous materials are not only of tremendous interest as catalysis or catalytic supports in processes involving large molecules which are unable to diffuse effectively through the smaller microporous channels of zeolites, but also to nanoelectronic devices, host-guest chemistry, and gas sorption processes. We have investigated the structure and dynamics of several transition metal surfactants~in particular, the 15N and 93Nb signals which exhibit lineshape changes due to motional processes.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR000995-21
Application #
5221948
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Marintchev, Assen; Edmonds, Katherine A; Marintcheva, Boriana et al. (2009) Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Cell 136:447-60
Frueh, Dominique P; Arthanari, Haribabu; Koglin, Alexander et al. (2009) A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins. J Am Chem Soc 131:12880-1
Frueh, Dominique P; Leed, Alison; Arthanari, Haribabu et al. (2009) Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in (15)N-(13)C-ILV methyl labeled proteins. J Biomol NMR 45:311-8
Lentz, Margaret R; Westmoreland, Susan V; Lee, Vallent et al. (2008) Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS. Magn Reson Med 59:475-84
Hyberts, Sven G; Heffron, Gregory J; Tarragona, Nestor G et al. (2007) Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction. J Am Chem Soc 129:5108-16
Chen, Jingyang; Dupradeau, Francois-Yves; Case, David A et al. (2007) Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites. Biochemistry 46:3096-107
Lentz, Margaret R; Kim, John P; Westmoreland, Susan V et al. (2005) Quantitative neuropathologic correlates of changes in ratio of N-acetylaspartate to creatine in macaque brain. Radiology 235:461-8
Kim, John P; Lentz, Margaret R; Westmoreland, Susan V et al. (2005) Relationships between astrogliosis and 1H MR spectroscopic measures of brain choline/creatine and myo-inositol/creatine in a primate model. AJNR Am J Neuroradiol 26:752-9
Mo, H; Dai, Y; Pochapsky, S S et al. (1999) 1H, 13C and 15N NMR assignments for a carbon monoxide generating metalloenzyme from Klebsiella pneumoniae. J Biomol NMR 14:287-8
Mo, H; Pochapsky, S S; Pochapsky, T C (1999) A model for the solution structure of oxidized terpredoxin, a Fe2S2 ferredoxin from Pseudomonas. Biochemistry 38:5666-75

Showing the most recent 10 out of 12 publications