X-ray studies of dUMP HMase are being pursued to address what structural features determine whether addition of water (dUMP HMase) or hydride transfer (TS) occurs to the exocyclic methylene of 5-CH2-dUMP. The high power and high flux of a synchrotron X-ray beam combined with rapid data collection capabilities make SSRL a valuable resource in surmounting the difficulties faced in the structural studies of dUMP HMase.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001209-22
Application #
6437457
Study Section
Project Start
2001-03-01
Project End
2002-02-28
Budget Start
Budget End
Support Year
22
Fiscal Year
2001
Total Cost
$143,176
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
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