This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.The SSRL BTP staff provides hands-on user training for the effective use of the SMB SAXS/D instrument. Users receive a short tutorial on the software for their choice of data collection system. All users now use Blu-ICE for non-time resolved data collection for both solution scattering studies and studies on partially oriented systems. They receive training on MarParse, the data processing program for solution scattering developed recently by the BTP staff. Users are instructed on the basics in solution x-ray scattering data analysis, such as inspecting data for possible radiation-induced aggregation, subtracting the background, and calculating radii of gyration. The data processing program Fit2D, developed at the European Synchrotron Radiation Facility, as well as Primus from EMBL-Hamburg are also covered upon request. Some introductory tutorials to the sophisticated solution scattering data interpretation software packages, developed by Dr. Svergun (EMBL-Hamburg) are also given. Practical advice is given on choice of experiment geometry and equipment, especially detector, and data collection strategy especially for minimizing radiation damage to help improve data quality. This is routinely done to new user groups and has been found useful also for experienced users.
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