The goal of this project is to characterize the performance of adsorptive separation systems to improve the design and operation of protein purification equipment and to provide better methods for scaling up bench separation processes. Nuclear magnetic resonance spectroscopy will be used to measure key separations parameters, including intraparticle diffusion coefficients and rates of adsorption. NMR spectroscopy will also be used to identify fluorinated derivatives of proteins, which will be used to study the role of competitive protein adsorption in adsorptive separations.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR002301-14
Application #
6281580
Study Section
Project Start
1998-04-01
Project End
1999-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
14
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
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