Fluorescence and reflectance studies at cytesctomy offer the opportunity for examining spectral characteristics of dysplasia, CIS in addition to TCC, which is otherwise not possible. Thes ex vivo data were taken minutes after bladder resection. Initial studies conducted with 370 nm and 400 nm excitation have shown that spectra are similar to those of in vivo data. The preliminary results of this study indicate that fluorescence and reflectance spectroscopy can detect TCC and CIS lesions. To detect flat dysplasia, the excitation wavelengths and probes need to be optimized. Reseacrh efforts are underway on these lines.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR002594-11
Application #
5224216
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
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