Interferometric methods have been used to monitor tissue surface movements of nanometer dimention in a nsec time scale. This has been used to study the onset of laser ablation. The results have been published in a series of publication published recently. The improved technique has allowed careful monitoring of laser-induced cavitation phenomenon in water with a temporal resolution of a few nanoseconds. This technique has also been applied to """"""""soft"""""""" tissue (meniscus) and it has been shown that cavitation occurs within meniscus. This technique is currently being used to determine the cavitation threshold (tensile strength) of water and saline.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR002594-15
Application #
6314213
Study Section
Project Start
2000-06-01
Project End
2001-05-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
15
Fiscal Year
2000
Total Cost
$13,842
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
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Dingari, Narahara Chari; Barman, Ishan; Myakalwar, Ashwin Kumar et al. (2012) Incorporation of support vector machines in the LIBS toolbox for sensitive and robust classification amidst unexpected sample and system variability. Anal Chem 84:2686-94

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