Complex flow, such as those associated with stenoses involves velocities, accelerations, and higher order motion moments, and is difficult to image by MRI. This is because spins flowing in the magnetic fields applied for imaging undergo dephasing and result in signal loss. Gradient moment nulling techniques compensate for velocities, but not acceleration and other higher order motions. We have developed a method to image and measure velocities in and near the turbulent jets produced by stenoses. The ultra-fast MR imaging technique, RUFIS (Rotating Ultra-Fast Imaging Sequence) that was developed in this Center has been used successfully to image """"""""turbulent puffs"""""""" and turbulent jets produced by a stenotic phantom. During the past year, we have extended our measurements to develop a method to measure flow velocities in and near the turbulent jets produced by stenoses. Velocity is encoded into the signal by a velocity encoding slice selection sequence applied prior to the RUFIS imaging sequence. Velocity encoded images are obtained for through-plane flow at the stenosos and at 1 cm upstream from it. Relative velocity contour maps with 0.67 mm resolution have been obtained for Reynolds numbers upto 2500.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR003631-09
Application #
5224627
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Ramachandran, Suchitra; Meyer, Travis; Olson, Carl R (2016) Prediction suppression in monkey inferotemporal cortex depends on the conditional probability between images. J Neurophysiol 115:355-62
Meyer, Travis; Walker, Christopher; Cho, Raymond Y et al. (2014) Image familiarization sharpens response dynamics of neurons in inferotemporal cortex. Nat Neurosci 17:1388-94
Hall, Nathan; Colby, Carol (2014) S-cone visual stimuli activate superior colliculus neurons in old world monkeys: implications for understanding blindsight. J Cogn Neurosci 26:1234-56
Subramanian, Janani; Colby, Carol L (2014) Shape selectivity and remapping in dorsal stream visual area LIP. J Neurophysiol 111:613-27
Berdyyeva, Tamara K; Olson, Carl R (2014) Intracortical microstimulation of supplementary eye field impairs ability of monkeys to make serially ordered saccades. J Neurophysiol 111:1529-40
Meyer, Travis; Ramachandran, Suchitra; Olson, Carl R (2014) Statistical learning of serial visual transitions by neurons in monkey inferotemporal cortex. J Neurosci 34:9332-7
Hall, Nathan; Colby, Carol (2013) Psychophysical definition of S-cone stimuli in the macaque. J Vis 13:
Leathers, Marvin L; Olson, Carl R (2012) In monkeys making value-based decisions, LIP neurons encode cue salience and not action value. Science 338:132-5
Meyer, Travis; Olson, Carl R (2011) Statistical learning of visual transitions in monkey inferotemporal cortex. Proc Natl Acad Sci U S A 108:19401-6
Berdyyeva, Tamara K; Olson, Carl R (2011) Relation of ordinal position signals to the expectation of reward and passage of time in four areas of the macaque frontal cortex. J Neurophysiol 105:2547-59

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