MR microscopy may contribute to understanding what happens when a foreign body is place in the body for purposes of either imaging or measuring the chemical environment. We will image, with implanted coils, the development of fibrous capsule on the silicone coating that surrounds the imaging coil. Imaging will be done at 1, 7, 14 and 28 days after implant. Following fixation, the coil and surrounding tissue will be removed and imaged ex vivo at higher resolution. Finally, the complex of fibrous capsule and coil will be imaged by conventional microscopy.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR005959-10
Application #
6220708
Study Section
Project Start
1999-09-15
Project End
2000-08-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
10
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
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