We propose pilot experiments to explore segregation and mixing in thin layers of granular material. This area is germane to a current hot topic in physics, math and engineering, namely granular materials. It is also an area of considerable technical interest, with relevance to the production of drugs. Segregation in granular materials has been made famous by the """"""""Brazil nut effect"""""""", but is important in many different settings, including shaking of thin horizontal layers of material. The pilot project would involve the construction of a simple experimental shaker container and coil. We would use organic materials of different sizes (poppy seeds and similar) that have been successfully imaged using MRI (i.e. Fukushima). The container would be vibrated in Bob Behringer's lab using existing equipment. As soon as the vibration is stopped, the grains effectively """"""""freeze"""""""", i.e., maintain their relative positions. We would then place the shaker in the magnet and carry out a 3D scan to determine the degree of internal segregation. We envision carrying out a modest number, - half a dozen, such scans in order to establish the validity of the technique. We would then actively pursue funding from the sources noted above, using the pilot scans as a demonstration of feasibility. At the same time, Igor Aronson and his collaborators would proceed with the development of new theoretical models.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR005959-12
Application #
6493730
Study Section
Project Start
2001-09-01
Project End
2002-08-31
Budget Start
Budget End
Support Year
12
Fiscal Year
2001
Total Cost
$288,015
Indirect Cost
Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
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