New dendrimer-based agents for blood pool contrast and targeting to cancer cells have been developed and tested in vitro and in vivo. Continuing studies of gel-based agents have revealed complex dynamic and morphological changes. A comprehensive theory of their effects on water relaxation has been developed and is under test.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR005964-09
Application #
6122338
Study Section
Project Start
1999-02-10
Project End
2000-01-14
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
9
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Li, Li; Palencia, Andrés; Lukk, Tiit et al. (2013) Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens. Proc Natl Acad Sci U S A 110:3817-22
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