With the aid of transgenic mice (in collaboration with Dr. Jeffrey Gordon, Washington University) expressing proteins, (p53,Kras and T-antigen) involved in tumorigenesis, in conjunction with cDNA's related to cell-cycle regulation (in collaboration with Dr. David Beach, Cold Spring Harbor); I intend to investigate the relationship among proteins, substrates and ligands in an attempt to elucidate temporal and spatial relationships essential for normal cellular proliferation and differentiation.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
3P41RR006009-08S1
Application #
2765173
Study Section
Project Start
Project End
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
8
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Mellon Pitts Corporation (Mpc Corp)
Department
Type
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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