This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Keywords: molecular biology, genomics Abstract: An advanced introduction to computational molecular biology, using an applied algorithms approach. The course will sruvey established algorithmic methods, including pairwise sequence alignment and dynamic programming, multiple sequence alignment, fast database search heuristics, hidden Markov models for molecular motifs, phylogeny reconstruction and gene finding. We will explore emerging computational problems in genomics through special topics lectures and course projects.
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