Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. During the past 4 years, we have challenged the limits of BOLD fMRI to the level of sub-millimeter structures (i.e. cortical columns) in humans and laminar specificity in the animal model. We have established that SE BOLD technique at high fields is more suitable for mapping columnar structures. Our strategy of employing high-field SE BOLD contrast has allowed us to explore, in addition to ODCs, orientation columns in the human brain, which were previously unmapped. Here, we will develop new capabilities for larger volume coverage for high-resolution fMRI acquisitions in humans as well as continued application and development of a high resolution animal fMRI model.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR008079-19
Application #
8362848
Study Section
Special Emphasis Panel (ZRG1-SBIB-S (40))
Project Start
2011-06-01
Project End
2012-05-31
Budget Start
2011-06-01
Budget End
2012-05-31
Support Year
19
Fiscal Year
2011
Total Cost
$30,257
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Herzberg, Max P; Hodel, Amanda S; Cowell, Raquel A et al. (2018) Risk taking, decision-making, and brain volume in youth adopted internationally from institutional care. Neuropsychologia 119:262-270
U?urbil, Kamil (2018) Imaging at ultrahigh magnetic fields: History, challenges, and solutions. Neuroimage 168:7-32
Foell, Jens; Palumbo, Isabella M; Yancey, James R et al. (2018) Biobehavioral threat sensitivity and amygdala volume: A twin neuroimaging study. Neuroimage 186:14-21
Magnitsky, Sergey; Pickup, Stephan; Garwood, Michael et al. (2018) Imaging of a high concentration of iron labeled cells with positive contrast in a rat knee. Magn Reson Med :
Lee, Byeong-Yeul; Zhu, Xiao-Hong; Woo, Myung Kyun et al. (2018) Interleaved 31 P MRS imaging of human frontal and occipital lobes using dual RF coils in combination with single-channel transmitter-receiver and dynamic B0 shimming. NMR Biomed 31:
Wilson, Sylia; Malone, Stephen M; Hunt, Ruskin H et al. (2018) Problematic alcohol use and hippocampal volume in a female sample: disentangling cause from consequence using a co-twin control study design. Psychol Med 48:1673-1684
Nelson, Brent G; Bassett, Danielle S; Camchong, Jazmin et al. (2017) Comparison of large-scale human brain functional and anatomical networks in schizophrenia. Neuroimage Clin 15:439-448
Bolan, Patrick J; Kim, Eunhee; Herman, Benjamin A et al. (2017) MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial. J Magn Reson Imaging 46:290-302
Lyzinski, Vince; Fishkind, Donniell E; Fiori, Marcelo et al. (2016) Graph Matching: Relax at Your Own Risk. IEEE Trans Pattern Anal Mach Intell 38:60-73
Ugurbil, Kamil (2016) What is feasible with imaging human brain function and connectivity using functional magnetic resonance imaging. Philos Trans R Soc Lond B Biol Sci 371:

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