This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are developing new approaches and probes for Carbon Dioxide sensing using the ability of CO2 to form carbamate complexes with certain heterocylic nuclei. Upon CO2 binding, fluorescence probes readily undergo changes in their abilty to intramolecular charge transfer, enabling CO2 concentrations to be determine
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