This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are developing both silver nanorods and triangles for applications in metal-enhanced fluorescence. We have developed 2 new approaches for the deposition of these nanostructures on glass substrates. These silver surfaces are able to enhance the fluorescence of fluorophores positioned at appropriate distances using protein spacer layers. We have tested these structures with both ICG and fluorescein, and have shown their ability to significantly enhance their spectral properties, much better than our recently reported silver-island films.
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