This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The bulk of our training efforts is one on one training by the beamline scientists for new users that come to use the beamline. Training will include background information on the technique itself, how to use the beamline and the instrument, how to analyze and interpret the data. BioCAT takes part in any facility-wide workshops that are organized by the APS and other institutions that covers techniques supported by BioCAT and these typically have a hands on component. The SAS summer school """"""""Beyond Rg"""""""", directed at PI's and post-docs and typically attracts 30-40 students of which 6 participated in a hands-on session on 18ID where they were introduced to data collection techniques for small-angle solution scattering. BioCAT also participates in the National X-ray/Neutron Summer School at Argonne and Oak Ridge National Laboratories. As part of this school, BioCAT hosted 8 graduate students in a hands-on session on beamline 18ID again for small angle x-ray scattering. In both of these workshops, BioCAT staff gave lectures in the formal section. Post-docs trained at the facility include Dr. Rita Graceffa, Dr. Fenggang Bian and Dr. Olga Antipova, and Dr. Naresh Kujala. We can also identify 9 post-docs and 34 new graduate students from outside user groups trained on the beamline in this reporting period. In addition, twelve undergraduate and six graduate IIT students have undergone training in fiber diffraction during this reporting period. The hope is that some of these individuals will be capable of building and operating new facilities in the future.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Biotechnology Resource Grants (P41)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1-BCMB-E (40))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Illinois Institute of Technology
Other Basic Sciences
Schools of Arts and Sciences
United States
Zip Code
Orgel, Joseph P R O; Sella, Ido; Madhurapantula, Rama S et al. (2017) Molecular and ultrastructural studies of a fibrillar collagen from octocoral (Cnidaria). J Exp Biol 220:3327-3335
Yazdi, Aliakbar Khalili; Vezina, Grant C; Shilton, Brian H (2017) An alternate mode of oligomerization for E. coli SecA. Sci Rep 7:11747
Sullivan, Brendan; Robison, Gregory; Pushkar, Yulia et al. (2017) Copper accumulation in rodent brain astrocytes: A species difference. J Trace Elem Med Biol 39:6-13
Morris, Martha Clare (2016) Nutrition and risk of dementia: overview and methodological issues. Ann N Y Acad Sci 1367:31-7
Robison, Gregory; Sullivan, Brendan; Cannon, Jason R et al. (2015) Identification of dopaminergic neurons of the substantia nigra pars compacta as a target of manganese accumulation. Metallomics 7:748-55
Gelfand, Paul; Smith, Randy J; Stavitski, Eli et al. (2015) Characterization of Protein Structural Changes in Living Cells Using Time-Lapsed FTIR Imaging. Anal Chem 87:6025-31
Liang, Wenguang G; Ren, Min; Zhao, Fan et al. (2015) Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. J Mol Biol 427:1345-1358
Zhou, Hao; Li, Shangyang; Badger, John et al. (2015) Modulation of HIV protease flexibility by the T80N mutation. Proteins 83:1929-39
Nobrega, R Paul; Arora, Karunesh; Kathuria, Sagar V et al. (2014) Modulation of frustration in folding by sequence permutation. Proc Natl Acad Sci U S A 111:10562-7
Jiao, Lianying; Ouyang, Songying; Shaw, Neil et al. (2014) Mechanism of the Rpn13-induced activation of Uch37. Protein Cell 5:616-30

Showing the most recent 10 out of 100 publications