Introduction: Conventional MR imaging is not optimal for real-time interventional use. Changes in imaging parameters can take tens of seconds to be reflected in the images. Switching between pulse sequence types requires tens of seconds. The imaging plane cannot be easily modified during continuous scanning. 2DFT imaging is inherently limited in temporal resolution, and display lag prohibits continuous motion or repositioning of devices.
The aims of real-time interactive MRI are to maximize temporal resolution, minimize display lag, and allow interactive control during continuous scanning. An interface such as this is the key to enabling the continuous repositioning of interventional devices as is possible with other guidance modalities. Methods/Results: We are collaborating with John Pauly and Adam Kerr in the department of Electrical Engineering to adapt their real-time reconstruction system which was developed for a standard whole body machine to our interventional system. We have investigated the use of circular EPI k-space trajectory for this purpose and have installed Quad Ross hypersparc processors on the sparc workstation. These processors improve our reconstruction and display rate dramatically. In contrast to fluoroscopic methods of evaluation, MR has no associated ionizing radiation and has the ability to acquire images in any plane. Conclusions: Real-time interactive MRI is a promising imaging method for interventional MRI. We are currently developing rapid imaging methods and will soon turn to a clinical evaluation of these methods.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR009784-05
Application #
6123006
Study Section
Project Start
1999-01-01
Project End
2000-07-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Maclaren, Julian; Aksoy, Murat; Ooi, Melvyn B et al. (2018) Prospective motion correction using coil-mounted cameras: Cross-calibration considerations. Magn Reson Med 79:1911-1921
Guo, Jia; Holdsworth, Samantha J; Fan, Audrey P et al. (2018) Comparing accuracy and reproducibility of sequential and Hadamard-encoded multidelay pseudocontinuous arterial spin labeling for measuring cerebral blood flow and arterial transit time in healthy subjects: A simulation and in vivo study. J Magn Reson Imaging 47:1119-1132
Taviani, Valentina; Alley, Marcus T; Banerjee, Suchandrima et al. (2017) High-resolution diffusion-weighted imaging of the breast with multiband 2D radiofrequency pulses and a generalized parallel imaging reconstruction. Magn Reson Med 77:209-220
Uecker, Martin; Lustig, Michael (2017) Estimating absolute-phase maps using ESPIRiT and virtual conjugate coils. Magn Reson Med 77:1201-1207
Kogan, Feliks; Hargreaves, Brian A; Gold, Garry E (2017) Volumetric multislice gagCEST imaging of articular cartilage: Optimization and comparison with T1rho. Magn Reson Med 77:1134-1141
Aksoy, Murat; Maclaren, Julian; Bammer, Roland (2017) Prospective motion correction for 3D pseudo-continuous arterial spin labeling using an external optical tracking system. Magn Reson Imaging 39:44-52
Tamir, Jonathan I; Uecker, Martin; Chen, Weitian et al. (2017) T2 shuffling: Sharp, multicontrast, volumetric fast spin-echo imaging. Magn Reson Med 77:180-195
Lai, Lillian M; Cheng, Joseph Y; Alley, Marcus T et al. (2017) Feasibility of ferumoxytol-enhanced neonatal and young infant cardiac MRI without general anesthesia. J Magn Reson Imaging 45:1407-1418
Bian, W; Tranvinh, E; Tourdias, T et al. (2016) In Vivo 7T MR Quantitative Susceptibility Mapping Reveals Opposite Susceptibility Contrast between Cortical and White Matter Lesions in Multiple Sclerosis. AJNR Am J Neuroradiol 37:1808-1815
Vos, Sjoerd B; Aksoy, Murat; Han, Zhaoying et al. (2016) Trade-off between angular and spatial resolutions in in vivo fiber tractography. Neuroimage 129:117-132

Showing the most recent 10 out of 446 publications