This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.In phase-contrast MRI (PC-MRI), the full field of view is not needed for flow quantitation, as outer tissue such as the chest wall is irrelevant to the flow measurement. It has been reported that SENSE may pose as a problem in correctly unaliasing the tissue due to coil sensitivity maps that do not match that of the aliased tissue in the full field of view. The reconstructed images will have artifacts that may compromise the accuracy of a flow experiment. We apply an autocalibrating sequence to PC-MRI for both aortic and pulmonary flow. We reconstruct the data using the GRAPPA method and then compare our measurements with SENSE. Through Bland-Altman statistical analysis, we show that autocalibrating sequences will have closer agreement than SENSE to conventional PC-MRI. The aortic flow measurements seemed to benefit more from GRAPPA than the pulmonary artery flow measurements because the aliased signal is stronger in the aorta cases. A clinical application of the autocalibrating PC-MRI sequence would be the natural extension of this work.
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