This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Guided by the Resource Directors and staff, the following students participated in MS Resource research under the Boston University Undergraduate Research Opportunities Program and programs for medical student research in the 2006-7 academic year. Boston University Chemistry Dept. students make presentations on their work at the annual Undergraduate Research Symposium. Undergraduates from other institutions are also eligible to conduct research at the Resource.Ms. Marina Belyayev was also a chemistry major and joined the Resource in spring 2004. She used electron capture dissociation FTMS spectra to differentiate between alpha-aspartic acid and beta-aspartic acid. The isomerization of alpha-aspartic acid is an aging phenomenon and may be related to protein-folding disorders. She presented a poster at the 2006 ASMS meeting on her characterization of a radical trap useful to explore the mechanism of ECD using a radical trap; the manuscript has been accepted for publication in JASMS. Ms. Belyayev graduated in May 2006 and in now attending medical school at Case Western University. She spent the summer 2006 at the Resource.Mr. Paul Romesser has worked under the direction of Resource collaborator Gerald Denis for several years. He has been closely involved in proteomics studies of Brd2 complexes. He has presented poster on his research at the 2005 Keystone Conference organized by Prof. Costello and Prof. Mann and at the 2007 ASMS meeting. For the summer of 2006, Mr. Romesser received special funding to allow him to work full time at the Resource and CPC. Mr. Romesser began his medical studies at BUSM in Fall 2006 but continues to carry out research at the Resource.Ms. Lindsay Hunting is an undergraduate in Materials Science and Engineering at MIT. She worked with Prof. Zaia for the summer 2006, learning about proteoglycans.
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