This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Some studies describe a difference in corpus callosum structure in patients with epilepsies. In addition, there are several studies which describe critical time points on the development of this structure. Epilepsies with well-defined etiology and onset offer an opportunity to examine the effects of early cortical disturbances on the development of the corpus callosum. In this study we want to examine the influence of age of onset of the epilepsy, the duration and lateralization of the seizure focus on the development of the corpus callosum. For this purpose, we performed T1-weighted MRI scans in about 150 patients with temporal lobe epilepsy (left and right hemispheric) as well as about 50 control subjects. All of the patients are clinically well-described in regard to onset of epilepsy, etiology and duration.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR013642-11
Application #
7724423
Study Section
Special Emphasis Panel (ZRG1-SBIB-L (40))
Project Start
2008-08-01
Project End
2009-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
11
Fiscal Year
2008
Total Cost
$2,576
Indirect Cost
Name
University of California Los Angeles
Department
Neurology
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Green, Shulamite A; Hernandez, Leanna M; Bowman, Hilary C et al. (2018) Sensory over-responsivity and social cognition in ASD: Effects of aversive sensory stimuli and attentional modulation on neural responses to social cues. Dev Cogn Neurosci 29:127-139
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