This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We consider attention to be a construct which includes three interrelated classes of dynamic precesses: 1) those involved in redirecting attention, 2) those which selectively process information according to the focus of attention, and 3) those which are involved in sustaining the focus of attention. Due to the dynamic nature of these processes, investigation of the underlying brain mechanisms requires analyses of the active brain regions and their temporal activation patterns. Through our progress in the preceding grant period and through collaborative projects, we have the ability to acquire electroencephalography (EEG), magnetoencephalography (MEG), brain anatomical magnetic resonance images (MRI) and functional MRI (fMRI);as well as the capability to integrate and analyze these multi-modal data in our laboratory. This has enabled us to improve our methods for electromagnetic source estimation (EMSE) of the brain sources of EEG and MEG, including characterization of the temporal activation patterns in these brain areas. We now have the ability to constrain the EMSE with anatomical MRI and to inform the locations of likely brain sources with fMRI data in the same subjects. fMRI also serves as a stand-alone functional neuroimaging method for exploring the brain systems involved in attention. The proposed project applies this integrated multidisciplinary approach to examination of the spatial distribution of brain areas involved in these attentional processes and characterization of the temporal dynamics of the brain systems involved.
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| Yang, Yaling; Joshi, Shantanu H; Jahanshad, Neda et al. (2017) Neural correlates of proactive and reactive aggression in adolescent twins. Aggress Behav 43:230-240 |
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| Agis, Daniel; Goggins, Maria B; Oishi, Kumiko et al. (2016) Picturing the Size and Site of Stroke With an Expanded National Institutes of Health Stroke Scale. Stroke 47:1459-65 |
| Levine, Andrew J; Soontornniyomkij, Virawudh; Achim, Cristian L et al. (2016) Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. J Neurovirol 22:431-41 |
| Flournoy, John C; Pfeifer, Jennifer H; Moore, William E et al. (2016) Neural Reactivity to Emotional Faces May Mediate the Relationship Between Childhood Empathy and Adolescent Prosocial Behavior. Child Dev 87:1691-1702 |
| Joshi, Shantanu H; Vizueta, Nathalie; Foland-Ross, Lara et al. (2016) Relationships Between Altered Functional Magnetic Resonance Imaging Activation and Cortical Thickness in Patients With Euthymic Bipolar I Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging 1:507-517 |
| Ordóñez, Anna E; Loeb, Frances F; Zhou, Xueping et al. (2016) Lack of Gender-Related Differences in Childhood-Onset Schizophrenia. J Am Acad Child Adolesc Psychiatry 55:792-9 |
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