Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Given the strong biophysical correlation of fMRI and NIRS, specifically BOLD with HbR and ASL with HbT, we hypothesize that a combination of NIRS and fMRI will further enhance the estimation of brain activation through filtering of the physiological interference. To establish the temporal and spatial correlation of NIRS and fMRI, we have performed simultaneous near-infrared spectroscopy (NIRS) along with BOLD (blood-oxygen level dependant) and ASL (arterial spin labeling)-based fMRI during an event-related motor activity in human subjects

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR014075-11
Application #
7957666
Study Section
Special Emphasis Panel (ZRG1-SBIB-L (40))
Project Start
2009-09-01
Project End
2010-05-31
Budget Start
2009-09-01
Budget End
2010-05-31
Support Year
11
Fiscal Year
2009
Total Cost
$163,562
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Gale, Eric M; Wey, Hsiao-Ying; Ramsay, Ian et al. (2018) A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism. Radiology 286:865-872
Jas, Mainak; Larson, Eric; Engemann, Denis A et al. (2018) A Reproducible MEG/EEG Group Study With the MNE Software: Recommendations, Quality Assessments, and Good Practices. Front Neurosci 12:530
Dahlgren, M K; Laifer, L M; VanElzakker, M B et al. (2018) Diminished medial prefrontal cortex activation during the recollection of stressful events is an acquired characteristic of PTSD. Psychol Med 48:1128-1138
van Erp, Theo G M; Walton, Esther; Hibar, Derrek P et al. (2018) Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry 84:644-654
Hari, Riitta; Baillet, Sylvain; Barnes, Gareth et al. (2018) IFCN-endorsed practical guidelines for clinical magnetoencephalography (MEG). Clin Neurophysiol 129:1720-1747
Van de Bittner, Genevieve C; Van de Bittner, Kyle C; Wey, Hsiao-Ying et al. (2018) Positron Emission Tomography Assessment of the Intranasal Delivery Route for Orexin A. ACS Chem Neurosci 9:358-368
Rivas-Grajales, Ana María; Sawyer, Kayle S; Karmacharya, Sarina et al. (2018) Sexually dimorphic structural abnormalities in major connections of the medial forebrain bundle in alcoholism. Neuroimage Clin 19:98-105
Kline, Emily R; Seidman, Larry J; Cornblatt, Barbara A et al. (2018) Depression and clinical high-risk states: Baseline presentation of depressed vs. non-depressed participants in the NAPLS-2 cohort. Schizophr Res 192:357-363
Rosas, H D; Wilkens, P; Salat, D H et al. (2018) Complex spatial and temporally defined myelin and axonal degeneration in Huntington disease. Neuroimage Clin 20:236-242
Strebl, Martin G; Yang, Jane; Isaacs, Lyle et al. (2018) Adamantane/Cucurbituril: A Potential Pretargeted Imaging Strategy in Immuno-PET. Mol Imaging 17:1536012118799838

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