This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dipolar magnetization offers an interesting alternative contrast mechanism for MR. At high field, the Dipolar echoes can be larger than the primary spin echo. A goal of the Resource is to implement these sequences at 750-MHz and evaluate their utility. These sequences have been implemented on both the 600 and 750 MHz instruments (and 400 MHz at Nottingham), demonstrating non-linear behavior as high fields are reached. This has been made the research highlight above for Core 2. In short, these are the highest field MSEs yet examined. Additionally, we have been able to model the non-linear signal behavior at longer distance scales.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
3P41RR016105-05S1
Application #
7369575
Study Section
Special Emphasis Panel (ZRG1)
Project Start
2005-05-01
Project End
2007-04-30
Budget Start
2005-05-01
Budget End
2007-04-30
Support Year
5
Fiscal Year
2006
Total Cost
$17,377
Indirect Cost
Name
University of Florida
Department
Neurosciences
Type
Schools of Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Flint, Jeremy J; Hansen, Brian; Blackband, Stephen J (2016) Diffusion tensor microscopy data (15.6 ?m in-plane) of white matter tracts in the human, pig, and rat spinal cord with corresponding tissue histology. Data Brief 9:271-4
Flint, Jeremy J; Hansen, Brian; Fey, Michael et al. (2010) Cellular-level diffusion tensor microscopy and fiber tracking in mammalian nervous tissue with direct histological correlation. Neuroimage 52:556-61
Flint, Jeremy; Hansen, Brian; Vestergaard-Poulsen, Peter et al. (2009) Diffusion weighted magnetic resonance imaging of neuronal activity in the hippocampal slice model. Neuroimage 46:411-8
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Kim, Jung Hwan; Astary, Garrett W; Chen, Xiaoming et al. (2009) Voxelized model of interstitial transport in the rat spinal cord following direct infusion into white matter. J Biomech Eng 131:071007
Tarver, Matthew R; Schmelz, Eric A; Rocca, James R et al. (2009) Effects of soldier-derived terpenes on soldier caste differentiation in the termite Reticulitermes flavipes. J Chem Ecol 35:256-64
Shepherd, Timothy M; Thelwall, Peter E; Stanisz, Greg J et al. (2009) Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue. Magn Reson Med 62:26-34

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