This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.In late 2003, ACERT acquired new 170 and 240GHz phase-locked, tracking millimeter-wave sources from Virginia Diodes, Inc. (VDI). With respect to our previous millimeter-wave sources, these sources feature reduced complexity (single PLL vs. dual PLL), increased power output (+12dB) and greatly expanded reference-to-output tracking range (fc +/- 5GHz vs. fc +/- 0.5GHz). However, these sources, due to their relatively high multiplier power levels, require exacting monitoring and control of the multiplier bias levels and a fast, reliable protective shut-down scheme for instances of out-of-spec operation. At maximum power levels, even a minor violation of the requisite multiplier bias conditions can result in a high-cost, long down-time source failure. Our goal in designing a universal bias driver and power supply for these sources is to provide a means of reproducing output power settings up to the maximum rated value, without incurring significant risk of source failure due to possible operator misadjustment of source operating parameters.To accomplish this goal, we have designed the multiplier bias sources to exhibit voltage-dependent impedance characteristics which are centered on a value which may be manually adjusted over the acceptable bias voltage range for the related multiplier stage. These ranges, along with the maximum permissible diode currents for each of the multiplier stages, are programmed into the respective bias driver sections. Any multiplier current exceeding its diode maximum rating immediately shuts down the source's active multiplier stage, effectively removing r.f. excitation from and protecting the passive millimeter-wave multiplier stages.We have completed bench tests on our initial 240GHz bias driver/power supply, which operates as anticipated, and we are presently constructing a second unit for the 170GHz VDI source. This new 170GHz bias driver/power supply will replace the simple interim bias network which is currently in place for lower-power experimental work.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR016292-07
Application #
7602645
Study Section
Special Emphasis Panel (ZRG1-BCMB-K (40))
Project Start
2007-09-01
Project End
2008-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
7
Fiscal Year
2007
Total Cost
$5,659
Indirect Cost
Name
Cornell University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
872612445
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Jain, Rinku; Vanamee, Eva S; Dzikovski, Boris G et al. (2014) An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ?. J Mol Biol 426:301-8
Pratt, Ashley J; Shin, David S; Merz, Gregory E et al. (2014) Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes. Proc Natl Acad Sci U S A 111:E4568-76
Georgieva, Elka R; Borbat, Peter P; Ginter, Christopher et al. (2013) Conformational ensemble of the sodium-coupled aspartate transporter. Nat Struct Mol Biol 20:215-21
Airola, Michael V; Sukomon, Nattakan; Samanta, Dipanjan et al. (2013) HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors. PLoS Biol 11:e1001479
Airola, Michael V; Huh, Doowon; Sukomon, Nattakan et al. (2013) Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling. J Mol Biol 425:886-901
Sun, Yan; Zhang, Ziwei; Grigoryants, Vladimir M et al. (2012) The internal dynamics of mini c TAR DNA probed by electron paramagnetic resonance of nitroxide spin-labels at the lower stem, the loop, and the bulge. Biochemistry 51:8530-41
Smith, Andrew K; Freed, Jack H (2012) Dynamics and ordering of lipid spin-labels along the coexistence curve of two membrane phases: an ESR study. Chem Phys Lipids 165:348-61
Yu, Renyuan Pony; Darmon, Jonathan M; Hoyt, Jordan M et al. (2012) High-Activity Iron Catalysts for the Hydrogenation of Hindered, Unfunctionalized Alkenes. ACS Catal 2:1760-1764
Gaffney, Betty J; Bradshaw, Miles D; Frausto, Stephen D et al. (2012) Locating a lipid at the portal to the lipoxygenase active site. Biophys J 103:2134-44
Dzikovski, Boris; Tipikin, Dmitriy; Freed, Jack (2012) Conformational distributions and hydrogen bonding in gel and frozen lipid bilayers: a high frequency spin-label ESR study. J Phys Chem B 116:6694-706

Showing the most recent 10 out of 72 publications