Abstract

The goal of this nonbiomedical project is to develop quantitative understanding of the destruction of hazardous chemicals by oxidation and hydrolysis in sub and Supercritical water. The focus is on examination of the reaction kinetics and products from laboratory- scale treatment of model compounds. Multiphase feeds will be characterized. Human cell essays will be used to determine mutagenic characteristics of incomplete products of oxidation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
3P42ES004675-13S1
Application #
6340894
Study Section
Project Start
1999-04-01
Project End
2001-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
13
Fiscal Year
2000
Total Cost
$175,274
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Diez, Sergi; Noonan, Gregory O; MacFarlane, John K et al. (2007) Ferrous iron oxidation rates in the pycnocline of a permanently stratified lake. Chemosphere 66:1561-70
Senn, David B; Gawel, James E; Jay, Jennifer A et al. (2007) Long-term fate of a pulse arsenic input to a eutrophic lake. Environ Sci Technol 41:3062-8
Risoul, Veronique; Richter, Henning; Lafleur, Arthur L et al. (2005) Effects of temperature and soil components on emissions from pyrolysis of pyrene-contaminated soil. J Hazard Mater 126:128-40
Coller, Hilary A; Khrapko, Konstantin; Herrero-Jimenez, Pablo et al. (2005) Clustering of mutant mitochondrial DNA copies suggests stem cells are common in human bronchial epithelium. Mutat Res 578:256-71
Pedersen, Daniel U; Durant, John L; Taghizadeh, Koli et al. (2005) Human cell mutagens in respirable airborne particles from the northeastern United States. 2. Quantification of mutagens and other organic compounds. Environ Sci Technol 39:9547-60
Durant, John L; Ivushkina, Tatiana; MacLaughlin, Kathy et al. (2004) Elevated levels of arsenic in the sediments of an urban pond: sources, distribution and water quality impacts. Water Res 38:2989-3000
Blute, Nicole Keon; Brabander, Daniel J; Hemond, Harold F et al. (2004) Arsenic sequestration by ferric iron plaque on cattail roots. Environ Sci Technol 38:6074-7
Pedersen, Daniel U; Durant, John L; Penman, Bruce W et al. (2004) Human-cell mutagens in respirable airborne particles in the northeastern United States. 1. Mutagenicity of fractionated samples. Environ Sci Technol 38:682-9
Southworth, Barbara A; Voelker, Bettina M (2003) Hydroxyl radical production via the photo-Fenton reaction in the presence of fulvic acid. Environ Sci Technol 37:1130-6
Tomita-Mitchell, Aoy; Ling, Losee Lucy; Glover, Curtis L et al. (2003) The mutational spectrum of the HPRT gene from human T cells in vivo shares a significant concordant set of hot spots with MNNG-treated human cells. Cancer Res 63:5793-8

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