The Training Core aims to produce doctoral level engineers and scientists with the interdisciplinary educational experience necessary to address complex research problems posed by hazardous waste sites. The Core, with 27 training faculty, will be directed by a committee of 6 experienced members spanning the disciplinary scope of the Superfund program and closely connected with other toxicology programs and a variety of graduate groups on campus. Our strong recruitment program in toxicological sciences is complemented by continued emphasis on nonbiological projects, for which the excellent UC Davis graduate programs in chemistry, engineering, hydrogeology and soil science are a great asset. While fulfilling course requirements of their respective graduate group programs, the students, from diverse backgrounds, will be encouraged in preparatory coursework to take advantage of an extensive menu of relevant courses to gain interdisciplinary expertise. In addition, their education will be enriched by (i) attendance at Superfund-supported series of campus seminars to be given by leading environmental health scientists; (ii) practical experience in the regulatory environment through research translation activities; (iii) presentations of their own research results at national meetings, at monthly meetings of Superfund investigators, at the annual Superfund tri-program meeting and at annual retreats/symposia co-sponsored with other toxicologically oriented campus programs; and (iv) special hands on training offered by the Analytical Core, the DNA Microarray, Proteomics and Metabolomics Core and facilities specializing in interdisciplinary research (Molecular Structure Facility, Center for Excellence in Environmental Engineering and Water Resources, John Muir Institute for the Environment). Selection of candidates for 4 trainee slots (university contribution) will be on the basis of academic credentials (GPA, recommendation letters) and a research proposal. Trainee progress will be monitored by periodic review of coursework, research summaries, participation in Superfund meetings, and timely fulfillment of academic requirements (e.g., qualifying examination). The Training Committee will also select applicants for the innovative Distinguished Undergraduate Summer Research Training Program, which promotes graduate school matriculation and careers in environmental health sciences with an emphasis on minority undergraduates.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004699-20
Application #
7311795
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
20
Fiscal Year
2006
Total Cost
$111,227
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Taha, Ameer Y; Hennebelle, Marie; Yang, Jun et al. (2018) Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins Leukot Essent Fatty Acids 138:71-80
Hill 3rd, Thomas; Rice, Robert H (2018) DUOX expression in human keratinocytes and bronchial epithelial cells: Influence of vanadate. Toxicol In Vitro 46:257-264
Kodani, Sean D; Wan, Debin; Wagner, Karen M et al. (2018) Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. ACS Omega 3:14076-14086
Ren, Qian; Ma, Min; Yang, Jun et al. (2018) Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease. Proc Natl Acad Sci U S A 115:E5815-E5823
Pecic, Stevan; Zeki, Amir A; Xu, Xiaoming et al. (2018) Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability. Prostaglandins Other Lipid Mediat 136:90-95
Yamanashi, Haruto; Boeglin, William E; Morisseau, Christophe et al. (2018) Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function. J Lipid Res 59:684-695
Wang, Fuli; Zhang, Hongyong; Ma, Ai-Hong et al. (2018) COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin. Mol Cancer Ther 17:474-483
Napimoga, M H; Rocha, E P; Trindade-da-Silva, C A et al. (2018) Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res 53:743-749
Blöcher, René; Wagner, Karen M; Gopireddy, Raghavender R et al. (2018) Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem 61:3541-3550
Hao, Lei; Kearns, Jamie; Scott, Sheyenne et al. (2018) Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther 365:467-475

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