Abstract

The Research Translation Core (RTC) formalizes functions that have been on-going in the UC Davis Superfund Basic Research and Training throughout its history. Partnering with governmental agencies, technology transfer, and communicating research information to broader audiences has been carried out on many fronts throughout the program. This core proposal seeks to capitalize on the strengths of the existing program in these areas, adds professional implementation and accountability, and proposes an innovative new cross-disciplinary model for the technology transfer. Core personnel will work on several fronts, with program personnel including investigators and students, campus administrators and staff responsible for research development, public relations and technology transfer, to develop coherent and practical plans to take research information and products to targeted constituencies and consumers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004699-21
Application #
7391805
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2007-04-01
Budget End
2008-03-31
Support Year
21
Fiscal Year
2007
Total Cost
$97,334
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Harris, Todd R; Kodani, Sean; Rand, Amy A et al. (2018) Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol 94:834-841
Bever, Candace S; Rand, Amy A; Nording, Malin et al. (2018) Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere 203:467-473
Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim et al. (2018) Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol 52:5469-5478
Lakkappa, Navya; Krishnamurthy, Praveen T; Yamjala, Karthik et al. (2018) Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal 149:457-464
Guedes, A G P; Aristizabal, F; Sole, A et al. (2018) Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis. J Vet Pharmacol Ther 41:230-238
Heikenfeld, J; Jajack, A; Rogers, J et al. (2018) Wearable sensors: modalities, challenges, and prospects. Lab Chip 18:217-248
Minaz, Nathani; Razdan, Rema; Hammock, Bruce D et al. (2018) An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats. Prostaglandins Other Lipid Mediat 136:84-89
Lassabe, Gabriel; Kramer, Karl; Hammock, Bruce D et al. (2018) Noncompetitive Homogeneous Detection of Small Molecules Using Synthetic Nanopeptamer-Based Luminescent Oxygen Channeling. Anal Chem 90:6187-6192
?ertíková Chábová, V?ra; Kujal, Petr; Škaroupková, Petra et al. (2018) Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. Kidney Blood Press Res 43:329-349
Kodani, Sean D; Bhakta, Saavan; Hwang, Sung Hee et al. (2018) Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett 28:762-768

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