The Training Core aims to produce doctoral level engineers and scientists with the interdisciplinary educational experience necessary to address complex research problems posed by hazardous waste sites. The Core, with 27 training faculty, will be directed by a committee of 6 experienced members spanning the disciplinary scope of the Superfund program and closely connected with other toxicology programs and a variety of graduate groups on campus. Our strong recruitment program in toxicological sciences is complemented by continued emphasis on nonbiological projects, for which the excellent UC Davis graduate programs in chemistry, engineering, hydrogeology and soil science are a great asset. While fulfilling course requirements of their respective graduate group programs, the students, from diverse backgrounds, will be encouraged in preparatory coursework to take advantage of an extensive menu of relevant courses to gain interdisciplinary expertise. In addition, their education will be enriched by (i) attendance at Superfund-supported series of campus seminars to be given by leading environmental health scientists;(ii) practical experience in the regulatory environment through research translation activities;(iii) presentations of their own research results at national meetings, at monthly meetings of Superfund investigators, at the annual Superfund tri-program meeting and at annual retreats/symposia co-sponsored with other toxicologically oriented campus programs;and (iv) special hands on training offered by the Analytical Core, the DNA Microarray, Proteomics and Metabolomics Core and facilities specializing in interdisciplinary research (Molecular Structure Facility, Center for Excellence in Environmental Engineering and Water Resources, John Muir Institute for the Environment). Selection of candidates for 4 trainee slots (university contribution) will be on the basis of academic credentials (GPA, recommendation letters) and a research proposal. Trainee progress will be monitored by periodic review of coursework, research summaries, participation in Superfund meetings, and timely fulfillment of academic requirements (e.g., qualifying examination). The Training Committee will also select applicants for the innovative Distinguished Undergraduate Summer Research Training Program, which promotes graduate school matriculation and careers in environmental health sciences with an emphasis on minority undergraduates.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004699-23
Application #
7795933
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
23
Fiscal Year
2009
Total Cost
$122,444
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Napimoga, M H; Rocha, E P; Trindade-da-Silva, C A et al. (2018) Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res 53:743-749
Blöcher, René; Wagner, Karen M; Gopireddy, Raghavender R et al. (2018) Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem 61:3541-3550
Hao, Lei; Kearns, Jamie; Scott, Sheyenne et al. (2018) Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther 365:467-475
Yang, Yang-Ming; Sun, Dong; Kandhi, Sharath et al. (2018) Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation. Proc Natl Acad Sci U S A 115:613-618
Zheng, Jing; Chen, Juan; Zou, Xiaohan et al. (2018) Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology 70:112-121
Cui, Xiping; Vasylieva, Natalia; Shen, Ding et al. (2018) Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. Analyst 143:2057-2065
Harris, Todd R; Kodani, Sean; Rand, Amy A et al. (2018) Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol 94:834-841
Bever, Candace S; Rand, Amy A; Nording, Malin et al. (2018) Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere 203:467-473
Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim et al. (2018) Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol 52:5469-5478
Lakkappa, Navya; Krishnamurthy, Praveen T; Yamjala, Karthik et al. (2018) Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal 149:457-464

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