Mine tailings disposal sites are prevalent in arid and semiarid regions throughout the world including the US Southwest. Unreclaimed mining wastes generally remain unvegetated for tens to hundreds of years, and exposed tailings can spread over vast areas via wind and water erosion. A combination of factors, including metal toxicity, low organic matter, acidic pH, high salinity, extreme temperatures, low precipitation, and severely stressed microbial communities contribute to this lack of vegetation. For such tailings, wind-borne dispersion is an important exposure route for nearby communities and environmentally sensitive areas. Specifically, tailings are a significant source of air pollution in the form of particulates <10 ?mu?m (PM10) and <2.5 ?mu?m (PM2.5). Exposure to these particulates has consequences for respiratory and other diseases even in the absence of toxic metals. The fact that many sites additionally contain toxic metals exacerbates the human health impact. A cost effective remedial technology for such sites is phytostabilization, the establishment of a permanent vegetative cover that does not accumulate metals into plant shoot tissues. While of great promise, there is currently little documentation of this technology in accessible scientific literature. The overall goal of this project is to determine how plant-microbe-metal interactions affect the short- and long-term requirements for, and mechanisms of, revegetation of arid mine tailings and to identify the biological and physico-chemical markers that indicate successful remediation. This project focuses on examining field application of phytostabilization while retaining several key basic research questions identified as important for success in the field. Specific objectives include: (1) to translate phytostabilization technology from the greenhouse to the field;(2) to determine if a multi-variate, spatial analysis of initial biophysico-chemical characteristics of mine tailings can serve as a useful predictor of phytostabilization success;(3) to evaluate the progress toward development of a """"""""healthy"""""""" soil as a function of time following revegetation of mine tailings;and (4) to determine the influence of microbial inocula on phytostabilization including plant biomass production and development of the rhizosphere community.

Public Health Relevance

This project is focused on developing sound scientific principles for field application of phytostablization as a cost-effective remedial technology for abandoned and active mine tailings sites in arid and semi-arid environments. Major outcomes will include basic information and tools needed to successfully apply phytostabilization to the range of mine tailings types found in arid regions which will result in reduced exposures for surrounding communities and ecosystems.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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University of Arizona
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Khan, Muhammad Amjad; Ding, Xiaodong; Khan, Sardar et al. (2018) The influence of various organic amendments on the bioavailability and plant uptake of cadmium present in mine-degraded soil. Sci Total Environ 636:810-817
Yellowhair, Monica; Romanotto, Michelle R; Stearns, Diane M et al. (2018) Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells. Toxicol Appl Pharmacol 349:29-38
Fu, Xiaori; Dionysiou, Dionysios D; Brusseau, Mark L et al. (2018) Enhanced effect of EDDS and hydroxylamine on Fe(II)-catalyzed SPC system for trichloroethylene degradation. Environ Sci Pollut Res Int 25:15733-15742
Duncan, Candice M; Brusseau, Mark L (2018) An assessment of correlations between chlorinated VOC concentrations in tree tissue and groundwater for phytoscreening applications. Sci Total Environ 616-617:875-880
Virgone, K M; Ramirez-Andreotta, M; Mainhagu, J et al. (2018) Effective integrated frameworks for assessing mining sustainability. Environ Geochem Health 40:2635-2655
Namdari, Soodabeh; Karimi, Neamat; Sorooshian, Armin et al. (2018) Impacts of climate and synoptic fluctuations on dust storm activity over the Middle East. Atmos Environ (1994) 173:265-276
Hossein Mardi, Ali; Khaghani, Ali; MacDonald, Alexander B et al. (2018) The Lake Urmia environmental disaster in Iran: A look at aerosol pollution. Sci Total Environ 633:42-49
Dehghani, Mansooreh; Fazlzadeh, Mehdi; Sorooshian, Armin et al. (2018) Characteristics and health effects of BTEX in a hot spot for urban pollution. Ecotoxicol Environ Saf 155:133-143
Pu, Mengjie; Guan, Zeyu; Ma, Yongwen et al. (2018) Synthesis of iron-based metal-organic framework MIL-53 as an efficient catalyst to activate persulfate for the degradation of Orange G in aqueous solution. Appl Catal A Gen 549:82-92
Brusseau, Mark L; Guo, Zhilin (2018) The integrated contaminant elution and tracer test toolkit, ICET3, for improved characterization of mass transfer, attenuation, and mass removal. J Contam Hydrol 208:17-26

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