The Outreach Core's broad, long-term objectives is to improve the communication, usefulness, and innovative development of Superfund- related environmental science and toxicant studies in two target areas: education and industry. The focus on education has four aims geared to transfer knowledge about Superfund toxicants and environmental health from UC San Diego's SBRP to several strategically selected high schools. Specifically, the four education aims are to provide and lead curriculum workshops for teachers and students, to develop Educational Outreach Resource Centers, to provide organized laboratory and field research apprenticeships, and to develop discipline, knowledge, communication, leadership, and mentoring skills. Methods to achieve these education aims include teacher workshops to develop curricula and hands-on student exercises including lab and field experience and an organized series of Technology Tours. The approach builds upon several nationally recognized watershed-based, educational initiatives underway at UCSD's Birch Aquarium and Natural Reserve System and at the San Diego's Natural History Museum. UCSD's Charter School and CREATE program, both of which operate as testbeds to develop innovative approaches to the education of disadvantaged students in grades 9-12, will actively participate in this effort. The Outreach Core's focus on industry has three aims integrated with the education component. First, to build capacity for innovative university-industry networking and collaboration in the creation, integration, and transfer of knowledge about the basic biological, chemical, and physical aspects of Superfund toxicants. Second, to cultivate industrial partners for education and research purposes. And third, to build a Federated Geographic Information System (GIS) useful for linking Superfund-related basic science to water quality and public health issues in the larger San Diego-Tijuana binational border region. To meet these Industrial Environmental Association (IEA), especially the IEA's working committees on Strategic Environmental Management, Hazardous Waste, and Maquiladoras (export oriented factories in Mexico).

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
Application #
Study Section
Special Emphasis Panel (ZES1-DPB-D (G3))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Diego
La Jolla
United States
Zip Code
McNulty, Reginald; Cardone, Giovanni; Gilcrease, Eddie B et al. (2018) Cryo-EM Elucidation of the Structure of Bacteriophage P22 Virions after Genome Release. Biophys J 114:1295-1301
Song, Na-Young; Zhu, Feng; Wang, Zining et al. (2018) IKK? inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways. Proc Natl Acad Sci U S A 115:E812-E821
Song, Isabelle Jingyi; Yang, Yoon Mee; Inokuchi-Shimizu, Sayaka et al. (2018) The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer 142:81-91
Hoffmann, Hanne; Pandolfi, Erica; Larder, Rachel et al. (2018) Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2, Causes Subfertility in Mice Via Distinct Mechanisms. Neuroendocrinology :
Dow, Michelle; Pyke, Rachel M; Tsui, Brian Y et al. (2018) Integrative genomic analysis of mouse and human hepatocellular carcinoma. Proc Natl Acad Sci U S A 115:E9879-E9888
Kim, Ju Youn; Garcia-Carbonell, Ricard; Yamachika, Shinichiro et al. (2018) ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P. Cell 175:133-145.e15
Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin et al. (2018) Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301-306
Fan, Weiwei; He, Nanhai; Lin, Chun Shi et al. (2018) ERR? Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1?/?-Deficient Muscle. Cell Rep 22:2521-2529
Brouha, Sharon S; Nguyen, Phirum; Bettencourt, Ricki et al. (2018) Increased severity of liver fat content and liver fibrosis in non-alcoholic fatty liver disease correlate with epicardial fat volume in type 2 diabetes: A prospective study. Eur Radiol 28:1345-1355
Hsu, Po-Kai; Takahashi, Yohei; Munemasa, Shintaro et al. (2018) Abscisic acid-independent stomatal CO2 signal transduction pathway and convergence of CO2 and ABA signaling downstream of OST1 kinase. Proc Natl Acad Sci U S A 115:E9971-E9980

Showing the most recent 10 out of 404 publications