Abstract

This analytical core laboratory will be housed at Lamont-Doherty Earth Observatory (LDEO) and will provide sample preparation and analyzes to five of the projects of this Superfund application (Project 1, Project 3, Project 5, Project 6, and Project 7). Sample preparation will include the following matrices: water, soil, sediment and pre-ashed blood. The instrumentation that will be used includes a VG sector 54-30 Thermal Ionization Mass Spectrometer (TIMS), a Hitachi Z8200 Graphite Furnace Atomic Absorption Spectrophotometer (GFAAS), a VG High-Resolution ICP-MS. Analyses to be performed for Projects 1 include stable isotope ratios on pre-ashed blood samples and soil samples and total arsenic concentrations for soil samples. Analyses to be performed for Project 3 include concentrations of As in drinking waters. Concentrations and speciation of arsenic in water and sediment samples will be measured for Projects 5, 6, and 7, as well as concentrations of redox-sensitive elements (e.g., Sb, Fe, Mn, U, Mo, Cd) in the same matrices. In addition, radionucleotide measurements via gamma spectroscopy will be made on sediment cores for Project 6.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
1P42ES010349-01
Application #
6323992
Study Section
Special Emphasis Panel (ZES1-DPB-D (G4))
Project Start
2000-06-01
Project End
2005-03-31
Budget Start
Budget End
Support Year
1
Fiscal Year
2000
Total Cost
$153,283
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Type
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Balakrishnan, Poojitha; Navas-Acien, Ana; Haack, Karin et al. (2018) Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study. Toxicol Appl Pharmacol 348:123-129
Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Jones, Miranda R; Tellez-Plaza, Maria; Vaidya, Dhananjay et al. (2018) Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA). J Expo Sci Environ Epidemiol :
Balakrishnan, Poojitha; Vaidya, Dhananjay; Voruganti, V Saroja et al. (2018) Genetic Variants Related to Cardiometabolic Traits Are Associated to B Cell Function, Insulin Resistance, and Diabetes Among AmeriCan Indians: The Strong Heart Family Study. Front Genet 9:466
Balakrishnan, Poojitha; Jones, Miranda R; Vaidya, Dhananjay et al. (2018) Ethnic, Geographic, and Genetic Differences in Arsenic Metabolism at Low Arsenic Exposure: A Preliminary Analysis in the Multi-Ethnic Study of Atherosclerosis (MESA). Int J Environ Res Public Health 15:
Flanagan, Sara V; Gleason, Jessie A; Spayd, Steven E et al. (2018) Health protective behavior following required arsenic testing under the New Jersey Private Well Testing Act. Int J Hyg Environ Health 221:929-940
Spratlen, Miranda J; Grau-Perez, Maria; Best, Lyle G et al. (2018) The Association of Arsenic Exposure and Arsenic Metabolism with the Metabolic Syndrome and its Individual Components: Prospective Evidence from the Strong Heart Family Study. Am J Epidemiol :
Niedzwiecki, Megan M; Liu, Xinhua; Zhu, Huiping et al. (2018) Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study. Environ Int 113:133-142
Shoenfelt, Elizabeth M; Winckler, Gisela; Lamy, Frank et al. (2018) Highly bioavailable dust-borne iron delivered to the Southern Ocean during glacial periods. Proc Natl Acad Sci U S A 115:11180-11185
Haque, Ezazul; Mailloux, Brian J; de Wolff, Daisy et al. (2018) Quantitative drinking water arsenic concentrations in field environments using mobile phone photometry of field kits. Sci Total Environ 618:579-585

Showing the most recent 10 out of 333 publications