; This analytical facility is housed at the Lamont-Doherty Earth Observatory of Columbia University. The Biogeochemistry Core will primarily support two biomedical projects and three non-biomedical projects, with additional support for the Community Engagement Core and the Research Translation Core. This support includes the analysis of ~24,000 groundwater samples by high-resolution inductively-couples mass spectrometry not only for As and Mn, on behalf of biomedical Projects 1 and 2, but also analysis of groundwater and sediment leaches for Na, Mg, Al, Si, P, S, K, Ca, Cr, Fe, Ni, Co, Cu, Zn, Mo, Cd, Sb, Ba, Pb and U on behalf of non-biomedical Projects 4, 5, 6, as well as the Community Engagement Core and the Research Translation Core. Core C also supports the analysis of exhaled breath condensate samples by liquid chromatography mass spectrometry for biomarkers collected for Project 2 and the determination of As speciation in a subset of groundwater and laboratory samples for the non-biomedical projects. For the analysis of the bulk chemistry of sediments from US Superfund sites and Bangladesh, the application of the latest generation of hand-held X-ray fluorescence analyzers will be systematically evaluated. Bulk organic carbon measurements in groundwater and sediment will also be supported under Core C.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES010349-13
Application #
8659447
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
13
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
Balakrishnan, Poojitha; Navas-Acien, Ana; Haack, Karin et al. (2018) Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study. Toxicol Appl Pharmacol 348:123-129
Oliver-Williams, Clare; Howard, Annie Green; Navas-Acien, Ana et al. (2018) Cadmium body burden, hypertension, and changes in blood pressure over time: results from a prospective cohort study in American Indians. J Am Soc Hypertens 12:426-437.e9
Jones, Miranda R; Tellez-Plaza, Maria; Vaidya, Dhananjay et al. (2018) Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA). J Expo Sci Environ Epidemiol :
Balakrishnan, Poojitha; Vaidya, Dhananjay; Voruganti, V Saroja et al. (2018) Genetic Variants Related to Cardiometabolic Traits Are Associated to B Cell Function, Insulin Resistance, and Diabetes Among AmeriCan Indians: The Strong Heart Family Study. Front Genet 9:466
Balakrishnan, Poojitha; Jones, Miranda R; Vaidya, Dhananjay et al. (2018) Ethnic, Geographic, and Genetic Differences in Arsenic Metabolism at Low Arsenic Exposure: A Preliminary Analysis in the Multi-Ethnic Study of Atherosclerosis (MESA). Int J Environ Res Public Health 15:
Flanagan, Sara V; Gleason, Jessie A; Spayd, Steven E et al. (2018) Health protective behavior following required arsenic testing under the New Jersey Private Well Testing Act. Int J Hyg Environ Health 221:929-940
Spratlen, Miranda J; Grau-Perez, Maria; Best, Lyle G et al. (2018) The Association of Arsenic Exposure and Arsenic Metabolism with the Metabolic Syndrome and its Individual Components: Prospective Evidence from the Strong Heart Family Study. Am J Epidemiol :
Niedzwiecki, Megan M; Liu, Xinhua; Zhu, Huiping et al. (2018) Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study. Environ Int 113:133-142
Shoenfelt, Elizabeth M; Winckler, Gisela; Lamy, Frank et al. (2018) Highly bioavailable dust-borne iron delivered to the Southern Ocean during glacial periods. Proc Natl Acad Sci U S A 115:11180-11185
Haque, Ezazul; Mailloux, Brian J; de Wolff, Daisy et al. (2018) Quantitative drinking water arsenic concentrations in field environments using mobile phone photometry of field kits. Sci Total Environ 618:579-585

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