The mission of the lowa Superfund Basic Research Program, Community Outreach Core (COC) is to address community concerns related to the sources, remediations and human impacts of hazardous chemicals, particularly PCBs, and to improve scientific literacy from the junior high to the adult level. To meet this mission, broad aims and specific objectives have been developed to facilitate coordinated activities between the COC personnel, the Community Advisory Boards and our partner schools in East Chicago, Indiana, Columbus Junction, lowa and Chicago, Illinois. The Community Advisory Board (CAB) in East Chicago feels that PCB contamination from industrial sources in the area is a potential community health issue. The dissemination of detailed PCB measurements in individuals, homes, schools and near the location of the soon to be constructed Confined Disposal Facility will empower the CAB to engage residents meaningfully. PCB contamination is currently of little concern to residents in Columbus Junction and Chicago, but CAB members and school officials in these communities are excited to be involved with the COC as a means to promote scientific literacy. With partner involvement, the COC will develop an Airborne PCB: Sources, Remediations, and Human Impacts science education module to be used in the classrooms of our partner schools and elsewhere. Additionally, the COC will develop a PCB Sustainability Case Study that will target teachers of first-year general education classes at colleges and universities. The case study method is an effective and well documented pedagogical tool and the PCB Sustainability Case Study will be widely distributed via the Electronic Hallway and by other internet teaching resource portals. Lastly, the COC will seek to engage Mississippi River communities that may be concerned with potential dredging of PCB-laden sediments for navigational purposes. Engaging additional communities will provide a means to expand the influence of the COC beyond our current partner list and determine if developed outreach materials have applicability on a wider, perhaps national, scale.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
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Special Emphasis Panel (ZES1-LWJ-M (O1))
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University of Iowa
Iowa City
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P?n?íková, Kate?ina; Brenerová, Petra; Svržková, Lucie et al. (2018) Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro. Environ Sci Pollut Res Int 25:16411-16419
Robertson, Larry W; Weber, Roland; Nakano, Takeshi et al. (2018) PCBs risk evaluation, environmental protection, and management: 50-year research and counting for elimination by 2028. Environ Sci Pollut Res Int 25:16269-16276
Klaren, William D; Vine, David; Vogt, Stefan et al. (2018) Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environ Sci Pollut Res Int 25:16427-16433
Tomsho, Kathryn S; Basra, Komal; Rubin, Staci M et al. (2018) Correction to: Community reporting of ambient air polychlorinated biphenyl concentrations near a Superfund site. Environ Sci Pollut Res Int 25:16401
Uwimana, Eric; Li, Xueshu; Lehmler, Hans-Joachim (2018) Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite. Environ Sci Technol 52:6000-6008
Herkert, Nicholas J; Hornbuckle, Keri C (2018) Effects of room airflow on accurate determination of PUF-PAS sampling rates in the indoor environment. Environ Sci Process Impacts 20:757-766
Herkert, Nicholas J; Spak, Scott N; Smith, Austen et al. (2018) Calibration and evaluation of PUF-PAS sampling rates across the Global Atmospheric Passive Sampling (GAPS) network. Environ Sci Process Impacts 20:210-219
Dhakal, Kiran; Gadupudi, Gopi S; Lehmler, Hans-Joachim et al. (2018) Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environ Sci Pollut Res Int 25:16277-16290
Enayah, Sabah H; Vanle, Brigitte C; Fuortes, Laurence J et al. (2018) PCB95 and PCB153 change dopamine levels and turn-over in PC12 cells. Toxicology 394:93-101
Klinefelter, Kelsey; Hooven, Molly Kromme; Bates, Chloe et al. (2018) Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders. Mamm Genome 29:112-127

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