The mission of the lowa Superfund Basic Research Program, Community Outreach Core (COC) is to address community concerns related to the sources, remediations and human impacts of hazardous chemicals, particularly PCBs, and to improve scientific literacy from the junior high to the adult level. To meet this mission, broad aims and specific objectives have been developed to facilitate coordinated activities between the COC personnel, the Community Advisory Boards and our partner schools in East Chicago, Indiana, Columbus Junction, lowa and Chicago, Illinois. The Community Advisory Board (CAB) in East Chicago feels that PCB contamination from industrial sources in the area is a potential community health issue. The dissemination of detailed PCB measurements in individuals, homes, schools and near the location of the soon to be constructed Confined Disposal Facility will empower the CAB to engage residents meaningfully. PCB contamination is currently of little concern to residents in Columbus Junction and Chicago, but CAB members and school officials in these communities are excited to be involved with the COC as a means to promote scientific literacy. With partner involvement, the COC will develop an Airborne PCB: Sources, Remediations, and Human Impacts science education module to be used in the classrooms of our partner schools and elsewhere. Additionally, the COC will develop a PCB Sustainability Case Study that will target teachers of first-year general education classes at colleges and universities. The case study method is an effective and well documented pedagogical tool and the PCB Sustainability Case Study will be widely distributed via the Electronic Hallway and by other internet teaching resource portals. Lastly, the COC will seek to engage Mississippi River communities that may be concerned with potential dredging of PCB-laden sediments for navigational purposes. Engaging additional communities will provide a means to expand the influence of the COC beyond our current partner list and determine if developed outreach materials have applicability on a wider, perhaps national, scale.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES013661-06
Application #
8249997
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
6
Fiscal Year
2011
Total Cost
$136,651
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Herkert, Nicholas J; Spak, Scott N; Smith, Austen et al. (2018) Calibration and evaluation of PUF-PAS sampling rates across the Global Atmospheric Passive Sampling (GAPS) network. Environ Sci Process Impacts 20:210-219
Dhakal, Kiran; Gadupudi, Gopi S; Lehmler, Hans-Joachim et al. (2018) Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environ Sci Pollut Res Int 25:16277-16290
Enayah, Sabah H; Vanle, Brigitte C; Fuortes, Laurence J et al. (2018) PCB95 and PCB153 change dopamine levels and turn-over in PC12 cells. Toxicology 394:93-101
Klinefelter, Kelsey; Hooven, Molly Kromme; Bates, Chloe et al. (2018) Genetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders. Mamm Genome 29:112-127
Gourronc, Francoise A; Robertson, Larry W; Klingelhutz, Aloysius J (2018) A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environ Sci Pollut Res Int 25:16481-16492
Alam, Sinthia; Carter, Gwendolyn S; Krager, Kimberly J et al. (2018) PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD. Antioxidants (Basel) 7:
Li, Xueshu; Holland, Erika B; Feng, Wei et al. (2018) Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environ Sci Pollut Res Int 25:16508-16521
Sethi, Sunjay; Keil, Kimberly P; Lein, Pamela J (2018) 3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism. Arch Toxicol 92:3337-3345
Parker, Victoria S; Squirewell, Edwin J; Lehmler, Hans-Joachim et al. (2018) Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environ Toxicol Pharmacol 58:196-201
Mattes, Timothy E; Ewald, Jessica M; Liang, Yi et al. (2018) PCB dechlorination hotspots and reductive dehalogenase genes in sediments from a contaminated wastewater lagoon. Environ Sci Pollut Res Int 25:16376-16388

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