Administrative Core The Iowa Superfund Research Program (ISRP) is a highly integrated research center focusing on the sources, exposures, toxicities, and remediation of polychlorinated biphenyl (PCBs) congeners in air. The center?s integration across biomedical and environmental science and engineering disciplines requires organizational infrastructure to enable the frequent, regular exchange of ideas, experiments, and data among projects and cores. The Admin?s Core?s major goal is to maintain a structure that promotes research integration, enables timely communication, and supports research translation that raises the quality and impact of center activities. The Admin Core provides vision and direction to ensure continued success in research and stakeholder engagement. To meet this goal, the Admin Core has three aims: 1) Provide program leadership and infrastructure to ensure synthesis of findings and integration of activities. Director Hornbuckle and Deputy Director Lehmler are leading environmental health researchers with backgrounds in environmental engineering and biomedical science, respectively. The ISRP Executive Committee, composed of leaders from every program component and representing diverse disciplines, works with Hornbuckle and Lehmler to ensure full integration and coordination among projects and cores. The leadership actively promotes frequent and regular researcher interactions both inside and outside the ISRP through monthly meetings, seminars, and events. The Admin Core conducts annual assessments of productivity and effectiveness for each project and core to guide recommendations from the External Advisory Committee (EAC), which is composed of nationally recognized Superfund researchers and other stakeholders. 2) Provide administrative and fiscal services, support, and oversight to ensure robust stewardship of available resources. The Director, together with the Center Administrator and Fiscal Manager, provide programmatic and financial services, support, and oversight. The ISRP is housed under and supported by IIHR?Hydroscience & Engineering, which has extensive experience managing multidisciplinary, multi-institutional projects ranging from thousands to tens of millions of dollars. 3) Disseminate ISRP scientific and environmental health discoveries through effective research translation. The ISRP is dedicated to making center research available and accessible in consideration of the SRP research translation objectives: a) communication with SRP and SRP staff; b) partnerships with government agencies; c) technology transfer; and d) information dissemination to other end-users, with a particular focus on communicating in the manner most appropriate for each audience. If the ISRP is renewed, regular activities will include the biennial International PCB Workshop; social media news feeds; webinars and training workshops; decision-support tools for agencies and organizations managing PCBs in schools; web applications to disseminate research findings; and development of new technology and platforms to maximize bi-directional communication.

Public Health Relevance

Administrative Core The major goal of the Iowa Superfund Research Program Administrative Core is to maintain a structure that: 1) promotes integration of research; 2) enables timely communication and research translation that raises the quality and impact of center activities; and 3) provides vision and direction to ensure the center?s continued success in conducting outstanding research stakeholder engagement. The Administrative Core provides administrative and fiscal services, support, and oversight to ensure robust stewardship of available resources.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
2P42ES013661-15
Application #
9839858
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
2025-01-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
15
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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P?n?íková, Kate?ina; Svržková, Lucie; Strapá?ová, Simona et al. (2018) In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion. Environ Pollut 237:473-486
P?n?íková, Kate?ina; Brenerová, Petra; Svržková, Lucie et al. (2018) Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro. Environ Sci Pollut Res Int 25:16411-16419
Robertson, Larry W; Weber, Roland; Nakano, Takeshi et al. (2018) PCBs risk evaluation, environmental protection, and management: 50-year research and counting for elimination by 2028. Environ Sci Pollut Res Int 25:16269-16276

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