This proposal describes a five year follow-up study of male and female adolescents at risk for developing alcohol problems and will test the 'Deviance Proneness' model of vulnerability for predicting pathological alcohol involvement. The Deviance Proneness theoretical model has often been cited as a pathway into pathological alcohol involvement, and eventually into alcohol dependence. Elements of the model theoretically related to the risk for developing alcohol-related problems, including temperament traits, behavior problems, cognitive functioning, and alcohol expectancies, will be examined in relation to a family history of alcohol dependence. Potential modifiers of alcohol/drug use behavior such as family and peer relations, gender, and coping ability will be also examined.
The aims of the new study derive from our previous studies and will focus on specific aspects of the model. This study will examine the utility of the Deviance Proneness model for predicting problematic drinking behaviors at two points in the adolescent's life. Using structural equation modeling methods, the model will first be tested using the Time 1 database when the subjects were in mid-adolescence ((16-17 years of age) to predict the initiation / maintenance of drinking behaviors and early alcohol problems. The follow-up data will be used to test the predictive value of the model as the subjects are entering early adulthood ((21-22 years of age) and are at maximal risk for heavy drinking and developing alcohol-related problems. The stability and efficiency of the model for predicting pathological alcohol involvement at these two points in time will also be examined. The proposed study builds upon and extends our previous work (UConn ARC Component II,1992-1997) with respect to the characterization of 275 male and female adolescent subjects at risk for alcoholism due to paternal alcoholism, and represents a 5-year follow- up of the current sample as they enter young adulthood This study should enhance our understanding of factors that contribute to the development and maintenance of drinking behavior and drinking problems among 'high risk' adolescents.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
5P50AA003510-25
Application #
6563116
Study Section
Project Start
2001-12-01
Project End
2002-11-30
Budget Start
Budget End
Support Year
25
Fiscal Year
2002
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
06030
Rash, Carla J; Petry, Nancy M; Alessi, Sheila M et al. (2018) Monitoring Alcohol Use in Heavy Drinking Soup Kitchen Attendees. Alcohol :
Rash, Carla J; Petry, Nancy M; Alessi, Sheila M (2018) A randomized trial of contingency management for smoking cessation in the homeless. Psychol Addict Behav 32:141-148
Rash, Carla J; Alessi, Sheila M; Petry, Nancy M (2017) Substance Abuse Treatment Patients in Housing Programs Respond to Contingency Management Interventions. J Subst Abuse Treat 72:97-102
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Rash, Carla J; Petry, Nancy M (2016) Gambling Disorder in the DSM-5: Opportunities to Improve Diagnosis and Treatment Especially in Substance Use and Homeless Populations. Curr Addict Rep 3:249-253
Meredith, Steven E; Alessi, Sheila M; Petry, Nancy M (2015) Smartphone applications to reduce alcohol consumption and help patients with alcohol use disorder: a state-of-the-art review. Adv Health Care Technol 1:47-54
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Ohannessian, Christine McCauley; Finan, Laura J; Schulz, Jessica et al. (2015) A Long-Term Longitudinal Examination of the Effect of Early Onset of Alcohol and Drug Use on Later Alcohol Abuse. Subst Abus 36:440-4
Sun, Jiangwen; Bi, Jinbo; Kranzler, Henry R (2014) Multiview comodeling to improve subtyping and genetic association of complex diseases. IEEE J Biomed Health Inform 18:548-54
Bi, Jinbo; Gelernter, Joel; Sun, Jiangwen et al. (2014) Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis. Am J Med Genet B Neuropsychiatr Genet 165B:148-56

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