The Pilot Project Component will continue into years 11-15 of the Indiana Alcohol Research Center. This Component is a mechanism for funding promising, innovative research, for attracting new investigators to alcohol research, for developing methodologies that may be of use to other investigators in the Center, and exploring areas of long-range relevance to the overall Center aims. This Component has had a major influence on the growth of alcohol research on this campus over the past 10 years. We believe that there has been a remarkable rate of success in obtaining independent funding subsequent to the receipt of pilot funding, for either new investigators or more senior ones who have entered new areas of research. Hence we propose to continue this component at the same level of activity as now exists. Two new pilots will be initiated in year 10 of the current funding period, and will continue into year 11. Thereafter, two new projects will be initiated in years 11 and 12, so that a total of four pilots are active each year. Additional pilots were received in excess of our ability to fund them, and these investigators, as well as other new investigators, are expected to submit applications for funding in years 13-15. The Pilot Project component is overseen by David Crabb with input from T. -K. Li and Richard Rose and the External Advisory Committee. Current and future pilots are chosen after posting notices of availability of funding and submission of a written application. Preference will continue to be given to new investigators first, established investigators new to alcohol research second, and lastly to established investigators in alcohol research. Progress is monitored by written yearly reports and presentation of results at the annual meeting or retreat.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Specialized Center (P50)
Project #
3P50AA007611-14S1
Application #
6500957
Study Section
Project Start
2001-09-17
Project End
2001-11-30
Budget Start
Budget End
Support Year
14
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
McClintick, Jeanette N; McBride, William J; Bell, Richard L et al. (2018) Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking. Alcohol 68:37-47
Houck, Christa A; Grahame, Nicholas J (2018) Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice. Psychopharmacology (Berl) 235:2167-2175
Ding, Zheng-Ming; Ingraham, Cynthia M; Hauser, Sheketha R et al. (2017) Reduced Levels of mGlu2 Receptors within the Prelimbic Cortex Are Not Associated with Elevated Glutamate Transmission or High Alcohol Drinking. Alcohol Clin Exp Res 41:1896-1906
Linsenbardt, David N; Smoker, Michael P; Janetsian-Fritz, Sarine S et al. (2017) Impulsivity in rodents with a genetic predisposition for excessive alcohol consumption is associated with a lack of a prospective strategy. Cogn Affect Behav Neurosci 17:235-251
Bell, Richard L; Hauser, Sheketha R; Liang, Tiebing et al. (2017) Rat animal models for screening medications to treat alcohol use disorders. Neuropharmacology 122:201-243
Öztürk, Nail Can; Resendiz, Marisol; Öztürk, Hakan et al. (2017) DNA Methylation program in normal and alcohol-induced thinning cortex. Alcohol 60:135-147
Ding, Zheng-Ming; Ingraham, Cynthia M; Rodd, Zachary A et al. (2016) Alcohol drinking increases the dopamine-stimulating effects of ethanol and reduces D2 auto-receptor and group II metabotropic glutamate receptor function within the posterior ventral tegmental area of alcohol preferring (P) rats. Neuropharmacology 109:41-48
Kasten, C R; Frazee, A M; Boehm 2nd, S L (2016) Developing a model of limited-access nicotine consumption in C57Bl/6J mice. Pharmacol Biochem Behav 148:28-37
Zhou, Feng C; Resendiz, Marisol; Lo, Chiao-Ling et al. (2016) Cell-Wide DNA De-Methylation and Re-Methylation of Purkinje Neurons in the Developing Cerebellum. PLoS One 11:e0162063
Qiu, Bin; Bell, Richard L; Cao, Yong et al. (2016) Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. J Genet Genomics 43:421-30

Showing the most recent 10 out of 253 publications