Abstract

The Biostatistics Core has four major responsibilities: 1) to provide statistical design and analysis consultation services to ADRC investigators; 2) to prepare the ADRC database for submission to the Alzheimer's Disease Data Coordinating Center; 3) to coordinate the entry, quality control and management of data generated by the Clinical and Neuropathology cores; and 4) to educate investigators trainees and junior facility in the principles and use of statistical analysis methodologies. Statistical consultation ranges from power analysis and the conduct of complex multivariate modeling. Data management and information distribution will be facilitated by the continued development of high-e4nd relational database systems accessible through a private Intranet.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
3P50AG005131-17S2
Application #
6398858
Study Section
Project Start
2000-09-20
Project End
2001-03-31
Budget Start
Budget End
Support Year
17
Fiscal Year
2000
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Type
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Kamara, Dennis M; Gangishetti, Umesh; Gearing, Marla et al. (2018) Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis 62:1815-1826
Zlatar, Zvinka Z; Muniz, Martha C; Espinoza, Sarah G et al. (2018) Subjective Cognitive Decline, Objective Cognition, and Depression in Older Hispanics Screened for Memory Impairment. J Alzheimers Dis 63:949-956
Urgolites, Zhisen J; Levy, Daniel A; Hopkins, Ramona O et al. (2018) Spared perception of object geometry and object components after hippocampal damage. Learn Mem 25:330-334
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Tulloch, Jessica; Leong, Lesley; Chen, Sunny et al. (2018) APOE DNA methylation is altered in Lewy body dementia. Alzheimers Dement 14:889-894
Alosco, Michael L; Sugarman, Michael A; Besser, Lilah M et al. (2018) A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis 63:1347-1360
Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia et al. (2018) Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. Lancet Neurol 17:64-74
Brent, Robert J (2018) Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia. Appl Econ 50:6327-6340
González, Hector M; Tarraf, Wassim; Harrison, Kimystian et al. (2018) Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results. Alzheimers Dement 14:579-589
Deming, Yuetiva; Dumitrescu, Logan; Barnes, Lisa L et al. (2018) Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol 136:857-872

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