The RTIT Core operates in different counties covering a large metropolitan area of about 11 million citizens and a one hundred square mile radius. The two sites (USC and UCI) have different but complementary strengths and have each enhanced the other in the approaches utilized in RTIT Core activities. The USC site has emphasized caregiver research, education and training, while the UCI site has emphasized research training and community education activities. Over the past five years, the RTIT core at USC has developed a special focus on understanding caregiver distress within a stress and coping framework and on reducing caregiver distress using stress reduction training techniques, research that is well grounded in tradition at USC. The general purpose of the outreach and training core is to bridge the gap between the research activities of the ADRC and the community. The outreach core serves an important function for the overall vitality of the center's activities through the accomplishment of the following objectives: facilitation of recruitment of subjects to the clinical cores; transferring advances in the filed and educating the community, caregivers, families, etc. on AD and related dementias; training new investigators for future clinical and basic science research in AD; and conducting caregivers research and training. At UCI, the major research training activities of the RTIT core to be highlighted in this document include weekly clinical core meetings, neurology grand rounds, the Academic Geriatric Research Program, various fellowships and clinical rotations, the Neuroscience Newsletter, the Neurobiology of Aging Training Grant, and various other research grants that emphasize training in the age-related domains. Major activities for information transfer to the community include the distinguished lecture series, the annual AD conference delivered in conjunction with the Alzheimer's Association of Orange County, the cross-cultural assessment battery for dementia, the caregiver training series, the adult activity programs, the ADRC Brain Aging Bulletin, and the Vietnamese outreach activities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005142-13
Application #
5204493
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Gallagher, Damien; Kiss, Alex; Lanctot, Krista L et al. (2018) Toward Prevention of Mild Cognitive Impairment in Older Adults With Depression: An Observational Study of Potentially Modifiable Risk Factors. J Clin Psychiatry 80:
Lin, Ming; Gong, Pinghua; Yang, Tao et al. (2018) Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord 32:18-27
Weissberger, Gali H; Nation, Daniel A; Nguyen, Caroline P et al. (2018) Meta-analysis of cognitive ability differences by apolipoprotein e genotype in young humans. Neurosci Biobehav Rev 94:49-58
Kirson, Noam Y; Scott Andrews, J; Desai, Urvi et al. (2018) Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis 61:295-307
Barnes, Josephine; Bartlett, Jonathan W; Wolk, David A et al. (2018) Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease. J Alzheimers Dis 64:631-642
Wang, Junyan; Aydogan, Dogu Baran; Varma, Rohit et al. (2018) Modeling topographic regularity in structural brain connectivity with application to tractogram filtering. Neuroimage 183:87-98
Joe, Elizabeth; Medina, Luis D; Ringman, John M et al. (2018) 1H MRS spectroscopy in preclinical autosomal dominant Alzheimer disease. Brain Imaging Behav :
Aydogan, Dogu Baran; Shi, Yonggang (2018) Tracking and validation techniques for topographically organized tractography. Neuroimage 181:64-84
Burke, Shanna L; Maramaldi, Peter; Cadet, Tamara et al. (2018) Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E. Int J Geriatr Psychiatry 33:200-211
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2018) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord 32:10-17

Showing the most recent 10 out of 590 publications