The Data Management and Statistics Core (Core C) of the Johns Hopkins Alzheimer's Disease Research Center (ADRC) has two overarching goals: (1) to provide database design, data management and data distribution for investigators associated with the ADRC, (2) to provide statistical expertise to investigators associated with the ADRC, including consultation to projects associated with the ADRC, development of novel analytic methods, and mentoring young statisticians. Through the provision of efficient database design and data management, Core C assures the accuracy, accessibility, and integration of data from the ADRC, and provides data sets to the National Alzheimer's Coordinating Center (NACC) and to investigators associated with the ADRC, both within the institution and at other ADC sites. Through the provision of high level statistical consultation to investigators associated with the Center, a range of projects related to the ADRC have been facilitated, novel methods have been developed, and young investigators have been trained in longitudinal methods related to cognitive decline and dementia. In the next funding cycle the Data Management and Statistics Core will continue with these aims.

Public Health Relevance

The Johns Hopkins Alzheimer's Disease Research Center (ADRC) will address many of the topics important to dementia research, with a particular focus on the understanding the earliest phases of Alzheimer's disease (AD). This approach is important if we are ultimately going to be able to diagnose and treat AD as early as possible. The ADRC fosters interactions among scientists who are pursuing this overarching theme.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
2P50AG005146-27
Application #
8013739
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4 (J2))
Project Start
Project End
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
27
Fiscal Year
2010
Total Cost
$163,690
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Chan, Carol K; Soldan, Anja; Pettigrew, Corinne et al. (2018) Depressive symptoms in relation to clinical symptom onset of mild cognitive impairment. Int Psychogeriatr :1-9
Wang, Qi; Guo, Lei; Thompson, Paul M et al. (2018) The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1. J Alzheimers Dis 64:149-169
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2018) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord 32:10-17
Ficek, Bronte N; Wang, Zeyi; Zhao, Yi et al. (2018) The effect of tDCS on functional connectivity in primary progressive aphasia. Neuroimage Clin 19:703-715
Wilmoth, Kristin; LoBue, Christian; Clem, Matthew A et al. (2018) Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment. Clin Neuropsychol 32:524-529
Warren, Kristen N; Beason-Held, Lori L; Carlson, Olga et al. (2018) Elevated Markers of Inflammation Are Associated With Longitudinal Changes in Brain Function in Older Adults. J Gerontol A Biol Sci Med Sci 73:770-778
Wang, Tingyan; Qiu, Robin G; Yu, Ming (2018) Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep 8:9161
Ting, Simon Kang Seng; Foo, Heidi; Chia, Pei Shi et al. (2018) Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia. J Neuropsychiatry Clin Neurosci 30:31-37
Eavani, Harini; Habes, Mohamad; Satterthwaite, Theodore D et al. (2018) Heterogeneity of structural and functional imaging patterns of advanced brain aging revealed via machine learning methods. Neurobiol Aging 71:41-50
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487

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