The purpose of this proposal is to describe the Memory and Aging Project Satellite which is designed to provide diagnosis and treatment of African American older adults in the St. Louis community. The primary goal of this program is to increase the participation of African American elderly in the ongoing activities of the Washington University Alzheimer's Disease Research Center. The major emphasis of the Satellite is to increase the recruitment and retention of African American elderly with DAT by the provision of supportive services which minimize the perceived barriers to participation among elderly blacks and their caregivers. A homebased model of service which links the ADRC with the St. Louis City Department of Health and the St. Louis Area Agency on Aging was developed in 1992. The diagnosis of DAT will be made by Marie Meisel R.N. using the usual clinical criteria defined by the Clinical Core. A family interview and functional assessment is also administered.The Clinical Core will provide the confirmation of the diagnosis , an estimated 20 African American subjects will be assessed by the Clinical Core each year. An additional 20 patients will be evaluated each year by the Barnes Neurology Clinic and added to the registry of African American elderly. The project will also document the effects of DAT on the families and community of African American elderly and assist in the development of ethnically sensitive and culturally appropriate community programs.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
3P50AG005681-16S1
Application #
6098091
Study Section
Project Start
1999-08-01
Project End
2000-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
16
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Strain, Jeremy F; Smith, Robert X; Beaumont, Helen et al. (2018) Loss of white matter integrity reflects tau accumulation in Alzheimer disease defined regions. Neurology 91:e313-e318
Roe, Catherine M; Babulal, Ganesh M; Stout, Sarah H et al. (2018) Using the A/T/N Framework to Examine Driving in Preclinical AD. Geriatrics (Basel) 3:
Qian, Winnie; Fischer, Corinne E; Schweizer, Tom A et al. (2018) Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease. Curr Alzheimer Res 15:187-194
Brent, Robert J (2018) Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia. Appl Econ 50:6327-6340
Suárez-Calvet, Marc; Capell, Anja; Araque Caballero, Miguel Ángel et al. (2018) CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med 10:
Gallagher, Damien; Kiss, Alex; Lanctot, Krista et al. (2018) Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression. Am J Geriatr Psychiatry 26:819-827
Ogren, Jennifer A; Tripathi, Raghav; Macey, Paul M et al. (2018) Regional cortical thickness changes accompanying generalized tonic-clonic seizures. Neuroimage Clin 20:205-215
Besser, Lilah; Kukull, Walter; Knopman, David S et al. (2018) Version 3 of the National Alzheimer's Coordinating Center's Uniform Data Set. Alzheimer Dis Assoc Disord 32:351-358
Aschenbrenner, Andrew J; Gordon, Brian A; Benzinger, Tammie L S et al. (2018) Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease. Neurology 91:e859-e866
Deming, Yuetiva; Dumitrescu, Logan; Barnes, Lisa L et al. (2018) Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol 136:857-872

Showing the most recent 10 out of 952 publications