Abstract

Core C: Data Management and Statistical Core Project Summary/Abstract The Database Management and Statistical Core (DMSC) will continue to serve as a resource and collaborator for all Projects and Cores related to the ADRC. Specifically, the DMSC will: (1) collaborate in the design of all Center forms and insure that the electronic versions of the forms allow simplicity of data entry as well as allow analysis files to be created and analyses to be accomplished; (2) work with the WU Center for Biomedical Informatics (CBMI) to make information collected by ADRC Cores and Projects available to all ADRC investigators through ClinPortal and CaTissue and to insure the quality control of all analysis data sets for publications; (3) collaborate with NACC to make smooth and timely data submissions (e.g., the Uniform Data Set); (4) lead and consult on the statistical design of all Projects with respect to the application of appropriate statistical and methodological techniques; (5) lead and collaborate in data analysis and report preparation; (6) facilitate local analyses and collaborations between and among ADCs and with NACC. ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005681-36
Application #
9697253
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
2021-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
36
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Schindler, Suzanne E; Gray, Julia D; Gordon, Brian A et al. (2018) Cerebrospinal fluid biomarkers measured by Elecsys assays compared to amyloid imaging. Alzheimers Dement 14:1460-1469
Roe, Catherine M; Babulal, Ganesh M; Mishra, Shruti et al. (2018) Tau and Amyloid Positron Emission Tomography Imaging Predict Driving Performance Among Older Adults with and without Preclinical Alzheimer's Disease. J Alzheimers Dis 61:509-513
Ibanez, Laura; Dube, Umber; Davis, Albert A et al. (2018) Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease. Front Neurosci 12:230
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2018) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord 32:10-17
Burke, Shanna L; Maramaldi, Peter; Cadet, Tamara et al. (2018) Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E. Int J Geriatr Psychiatry 33:200-211
Agogo, George O; Ramsey, Christine M; Gnjidic, Danijela et al. (2018) Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr 30:1477-1487
Lucey, Brendan P; Hicks, Terry J; McLeland, Jennifer S et al. (2018) Effect of sleep on overnight cerebrospinal fluid amyloid ? kinetics. Ann Neurol 83:197-204
Armstrong, Richard A; McKee, Ann C; Stein, Thor D et al. (2018) Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change. Neurol Sci :
Broce, Iris; Karch, Celeste M; Wen, Natalie et al. (2018) Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med 15:e1002504
Wilmoth, Kristin; LoBue, Christian; Clem, Matthew A et al. (2018) Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment. Clin Neuropsychol 32:524-529

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